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1
Comparative physical and genetic maps of the virulence plasmids of Salmonella enterica serovars typhimurium, enteritidis, choleraesuis, and dublin.肠炎沙门氏菌鼠伤寒血清型、肠炎血清型、猪霍乱血清型和都柏林血清型毒力质粒的比较物理图谱和遗传图谱。
Infect Immun. 1999 May;67(5):2611-4. doi: 10.1128/IAI.67.5.2611-2614.1999.
2
Pathogenicity differences of Salmonella enterica serovars Typhimurium, Enteritidis, and Choleraesuis-specific virulence plasmids and clinical S. Choleraesuis strains with large plasmids to the human THP-1 cell death.鼠伤寒沙门氏菌、肠炎沙门氏菌和猪霍乱沙门氏菌特异性毒力质粒以及具有大质粒的临床猪霍乱沙门氏菌菌株对人 THP-1 细胞死亡的致病性差异。
Microb Pathog. 2019 Mar;128:69-74. doi: 10.1016/j.micpath.2018.12.035. Epub 2018 Dec 22.
3
Nucleotide and amino acid sequences of oriT-traM-traJ-traY-traA-traL regions and mobilization of virulence plasmids of Salmonella enterica serovars enteritidis, gallinarum-pullorum, and typhimurium.肠炎沙门氏菌、鸡沙门氏菌和鼠伤寒沙门氏菌的oriT-traM-traJ-traY-traA-traL区域的核苷酸和氨基酸序列以及毒力质粒的转移
J Bacteriol. 2002 Jun;184(11):2857-62. doi: 10.1128/JB.184.11.2857-2862.2002.
4
Salmonella virulence plasmid. Modular acquisition of the spv virulence region by an F-plasmid in Salmonella enterica subspecies I and insertion into the chromosome of subspecies II, IIIa, IV and VII isolates.沙门氏菌毒力质粒。肠炎沙门氏菌亚种I中F质粒对spv毒力区域的模块化获得以及在亚种II、IIIa、IV和VII分离株染色体中的插入。
Genetics. 1998 Jul;149(3):1183-90. doi: 10.1093/genetics/149.3.1183.
5
Complete nucleotide sequence of a virulence plasmid of Salmonella enterica serovar Dublin and its phylogenetic relationship to the virulence plasmids of serovars Choleraesuis, Enteritidis and Typhimurium.肠炎沙门氏菌都柏林血清型毒力质粒的完整核苷酸序列及其与猪霍乱沙门氏菌、肠炎沙门氏菌和鼠伤寒沙门氏菌血清型毒力质粒的系统发育关系。
FEMS Microbiol Lett. 2008 May;282(1):39-43. doi: 10.1111/j.1574-6968.2008.01096.x. Epub 2008 Mar 10.
6
Identification of contemporary plasmid virulence genes in ancestral isolates of Salmonella enteritidis and Salmonella typhimurium.肠炎沙门氏菌和鼠伤寒沙门氏菌原始分离株中当代质粒毒力基因的鉴定。
FEMS Microbiol Lett. 1991 May 1;64(1):7-11. doi: 10.1016/0378-1097(91)90200-t.
7
Restriction map of the Salmonella enteritidis virulence plasmid and its homology with the plasmid of Salmonella typhimurium.肠炎沙门氏菌毒力质粒的限制酶切图谱及其与鼠伤寒沙门氏菌质粒的同源性。
Microb Pathog. 1994 Feb;16(2):165-9. doi: 10.1006/mpat.1994.1017.
8
The virulence plasmids of Salmonella serovars typhimurium, choleraesuis, dublin, and enteritidis, and the cryptic plasmids of Salmonella serovars copenhagen and sendai belong to the same incompatibility group, but not those of Salmonella serovars durban, gallinarum, give, infantis and pullorum.鼠伤寒沙门氏菌、猪霍乱沙门氏菌、都柏林沙门氏菌和肠炎沙门氏菌的毒力质粒，以及哥本哈根沙门氏菌和仙台沙门氏菌的隐蔽质粒属于同一不相容群，但都柏林沙门氏菌、鸡沙门氏菌、吉韦沙门氏菌、婴儿沙门氏菌和鸡白痢沙门氏菌的质粒不属于该不相容群。
Microb Pathog. 1990 Feb;8(2):101-7. doi: 10.1016/0882-4010(90)90074-z.
9
Large drug resistance virulence plasmids of clinical isolates of Salmonella enterica serovar Choleraesuis.肠炎沙门氏菌猪霍乱血清型临床分离株的大型耐药毒力质粒
Antimicrob Agents Chemother. 2001 Aug;45(8):2299-303. doi: 10.1128/AAC.45.8.2299-2303.2001.
10
Presence of F-like OriT base-pair sequence on the virulence plasmids of Salmonella serovars Gallinarum, Enteritidis, and Typhimurium, but absent in those of Choleraesuis and Dublin.鸡沙门氏菌、肠炎沙门氏菌和鼠伤寒沙门氏菌的毒力质粒上存在F样转移起始位点（OriT）碱基对序列，但猪霍乱沙门氏菌和都柏林沙门氏菌的毒力质粒上不存在该序列。
Microb Pathog. 1994 Jul;17(1):13-21. doi: 10.1006/mpat.1994.1048.

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Antimicrobial resistance and plasmid-associated virulence genes in isolated from pigs, pork, and humans in border provinces of Thailand and neighboring countries.从泰国边境省份及周边国家的猪、猪肉和人类中分离出的抗菌药物耐药性及质粒相关毒力基因
PeerJ. 2025 Aug 25;13:e19884. doi: 10.7717/peerj.19884. eCollection 2025.
2
Serovars and Vaccination Effect on the Immune Responses of Male and Female Layers.血清型及疫苗接种对蛋鸡（雌、雄）免疫反应的影响
J Poult Sci. 2016 Oct 25;53(4):318-328. doi: 10.2141/jpsa.0150167.
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Genomic comparison of diverse Salmonella serovars isolated from swine.从猪身上分离的不同血清型沙门氏菌的基因组比较。
PLoS One. 2019 Nov 1;14(11):e0224518. doi: 10.1371/journal.pone.0224518. eCollection 2019.
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Virulence Factors in Salmonella Typhimurium: The Sagacity of a Bacterium.鼠伤寒沙门氏菌的毒力因子：细菌的智慧。
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The influences of SE infection on layers' production performance, egg quality and blood biochemical indicators.SE 感染对产蛋层生产性能、蛋品质和血液生化指标的影响。
J Anim Sci Biotechnol. 2014 Jan 9;5(1):4. doi: 10.1186/2049-1891-5-4.
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Multiplicity of Salmonella entry mechanisms, a new paradigm for Salmonella pathogenesis.沙门氏菌进入机制的多样性：沙门氏菌发病机制的新范例。
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Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis and pathogenic convergence with Salmonella typhi.副伤寒沙门氏菌C：与猪霍乱沙门氏菌的遗传分化及与伤寒沙门氏菌的致病趋同
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8
Epidemiological characteristics of Salmonella Typhimurium isolated from animals and feed in Poland.从波兰动物和饲料中分离出的鼠伤寒沙门氏菌的流行病学特征。
Epidemiol Infect. 2006 Feb;134(1):179-85. doi: 10.1017/S0950268805004838.
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Correlation of phenotype with the genotype of egg-contaminating Salmonella enterica serovar Enteritidis.鸡蛋污染肠炎沙门氏菌肠炎血清型的表型与基因型的相关性。
Appl Environ Microbiol. 2005 Aug;71(8):4388-99. doi: 10.1128/AEM.71.8.4388-4399.2005.
10
The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen.猪霍乱沙门氏菌的基因组序列，一种具有高度侵袭性和耐药性的人畜共患病原体。
Nucleic Acids Res. 2005 Mar 21;33(5):1690-8. doi: 10.1093/nar/gki297. Print 2005.

本文引用的文献

1
The presence of genes homologous to the K88 genes faeH and faeI on the virulence plasmid of Salmonella gallinarum.鸡沙门氏菌毒力质粒上存在与K88基因faeH和faeI同源的基因。
FEMS Microbiol Lett. 1998 Feb 15;159(2):255-60. doi: 10.1111/j.1574-6968.1998.tb12869.x.
2
Genetic map of the virulence plasmid of Salmonella enteritidis and nucleotide sequence of its replicons.肠炎沙门氏菌毒力质粒的遗传图谱及其复制子的核苷酸序列。
Gene. 1997 Mar 25;188(1):53-61. doi: 10.1016/s0378-1119(96)00776-7.
3
Rapid identification of Salmonella serovars in feces by specific detection of virulence genes, invA and spvC, by an enrichment broth culture-multiplex PCR combination assay.通过富集肉汤培养-多重聚合酶链反应联合检测法特异性检测毒力基因invA和spvC，快速鉴定粪便中的沙门氏菌血清型。
J Clin Microbiol. 1996 Oct;34(10):2619-22. doi: 10.1128/jcm.34.10.2619-2622.1996.
4
Molecular analysis of spv virulence genes of the Salmonella virulence plasmids.沙门氏菌毒力质粒spv毒力基因的分子分析
Mol Microbiol. 1993 Mar;7(6):825-30. doi: 10.1111/j.1365-2958.1993.tb01172.x.
5
The parVP region of the Salmonella typhimurium virulence plasmid pSLT contains four loci required for incompatibility and partition.鼠伤寒沙门氏菌毒力质粒pSLT的parVP区域包含四个不亲和性和分配所需的基因座。
Plasmid. 1993 Jul;30(1):30-8. doi: 10.1006/plas.1993.1031.
6
Nucleotide sequence of a 13.9 kb segment of the 90 kb virulence plasmid of Salmonella typhimurium: the presence of fimbrial biosynthetic genes.鼠伤寒沙门氏菌90kb毒力质粒13.9kb片段的核苷酸序列：菌毛生物合成基因的存在
Mol Microbiol. 1993 May;8(3):543-58. doi: 10.1111/j.1365-2958.1993.tb01599.x.
7
Presence of F-like OriT base-pair sequence on the virulence plasmids of Salmonella serovars Gallinarum, Enteritidis, and Typhimurium, but absent in those of Choleraesuis and Dublin.鸡沙门氏菌、肠炎沙门氏菌和鼠伤寒沙门氏菌的毒力质粒上存在F样转移起始位点（OriT）碱基对序列，但猪霍乱沙门氏菌和都柏林沙门氏菌的毒力质粒上不存在该序列。
Microb Pathog. 1994 Jul;17(1):13-21. doi: 10.1006/mpat.1994.1048.
8
Rapid procedure for detection and isolation of large and small plasmids.用于检测和分离大小质粒的快速方法。
J Bacteriol. 1981 Mar;145(3):1365-73. doi: 10.1128/jb.145.3.1365-1373.1981.
9
Evidence of correlation between 50-kilobase plasmid of Salmonella choleraesuis and its virulence.猪霍乱沙门氏菌50千碱基质粒与其毒力之间的相关性证据。
Microb Pathog. 1988 Feb;4(2):155-63. doi: 10.1016/0882-4010(88)90057-5.
10
Plasmid-associated virulence of Salmonella enteritidis.肠炎沙门氏菌的质粒相关毒力
Microb Pathog. 1988 May;4(5):385-91. doi: 10.1016/0882-4010(88)90066-6.

肠炎沙门氏菌鼠伤寒血清型、肠炎血清型、猪霍乱血清型和都柏林血清型毒力质粒的比较物理图谱和遗传图谱。

Comparative physical and genetic maps of the virulence plasmids of Salmonella enterica serovars typhimurium, enteritidis, choleraesuis, and dublin.

作者信息

Chu C, Hong S F, Tsai C, Lin W S, Liu T P, Ou J T

机构信息

Department of Microbiology and Immunology, Chang Gung University College of Medicine, Kweishan, Taoyuan, Taiwan.

出版信息

Infect Immun. 1999 May;67(5):2611-4. doi: 10.1128/IAI.67.5.2611-2614.1999.

DOI:10.1128/IAI.67.5.2611-2614.1999
PMID:10225928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC116011/
Abstract

Using fragment profiling, PCR, and Southern hybridization, we found that Salmonella enterica serovar Choleraesuis harbored virulence plasmids of various sizes, whereas serovars Typhimurium, Enteritidis, and Dublin carried a plasmid of a unique size. Also, the virulence plasmid of Typhimurium contained genes in the same order detected in the other three plasmids, all of which contained deletions.

摘要

通过片段分析、聚合酶链反应（PCR）和Southern杂交，我们发现猪霍乱沙门氏菌携带各种大小的毒力质粒，而鼠伤寒沙门氏菌、肠炎沙门氏菌和都柏林沙门氏菌携带单一大小的质粒。此外，鼠伤寒沙门氏菌的毒力质粒所含基因的排列顺序与其他三种质粒中检测到的相同，所有这些质粒都有缺失。