Beutler Bryce D, Nguyen Emilie T, Parker Rex A, Tran Clement, Acharya Jay, Torres Fernando A, Gullapalli Nageshwara
University of Nevada, Reno School of Medicine, Reno, NV, USA.
Kaiser Permanente Los Angeles Medical Center, Department of Diagnostic Imaging, Los Angeles, CA, USA.
Radiol Case Rep. 2019 Nov 15;15(2):110-116. doi: 10.1016/j.radcr.2019.10.027. eCollection 2020 Feb.
Meningioma represents the most frequently diagnosed primary brain tumor, accounting for over one-third of central nervous system neoplasms. The majority of tumors are categorized as benign. However, albeit rarely, meningiomas may metastasize to distant sites. We describe a 78-year-old man with a history of recurrent World Health Organization grade I meningioma managed who presented for evaluation of weakness and urinary retention. A computed tomography scan obtained in the emergency department revealed multiple scattered low-density liver lesions. Subsequent magnetic resonance imaging showed a 5.5-centimeter heterogeneous enhancing mass with 2 smaller enhancing lesions suspicious for a primary or secondary malignant neoplasm. Microscopic examination of a tissue sample obtained via liver biopsy demonstrated a metastatic spindle cell neoplasm with histologic features compatible with a diagnosis of World Health Organization grade I transitional meningioma. The patient was referred to hematology/oncology for systemic therapy.
脑膜瘤是最常被诊断出的原发性脑肿瘤,占中枢神经系统肿瘤的三分之一以上。大多数肿瘤被归类为良性。然而,尽管很少见,脑膜瘤可能会转移到远处。我们描述了一名78岁男性,有复发性世界卫生组织I级脑膜瘤病史,因出现乏力和尿潴留前来评估。急诊科的计算机断层扫描显示肝脏有多个散在的低密度病变。随后的磁共振成像显示一个5.5厘米的不均匀强化肿块,伴有2个较小的强化病变,怀疑为原发性或继发性恶性肿瘤。通过肝脏活检获得的组织样本的显微镜检查显示为转移性梭形细胞瘤,其组织学特征与世界卫生组织I级过渡性脑膜瘤的诊断相符。该患者被转诊至血液科/肿瘤科进行全身治疗。