van der Gaag I, van den Ingh T S, Lamers C B, Lindeman J
Institute of Veterinary Pathology, Utrecht, The Netherlands.
Vet Q. 1988 Jul;10(3):151-5. doi: 10.1080/01652176.1988.9694164.
Zollinger-Ellison Syndrome in a 12-year old castrated male European Shorthair cat is described. The clinical symptoms were vomiting, weight loss, listlessness and alternating diarrhoea and obstipation. An endocrine tumour near the pancreatic duct had metastasised to the liver. Many duodenal ulcers were present. Immunohistochemistry revealed cells positive for gastrin and neuron-specific enolase (NSE) scattered throughout the tumour.
本文描述了一只12岁去势雄性欧洲短毛猫的佐林格-埃利森综合征。临床症状包括呕吐、体重减轻、倦怠以及腹泻与便秘交替出现。胰腺导管附近的内分泌肿瘤已转移至肝脏。存在多处十二指肠溃疡。免疫组织化学显示，整个肿瘤中散在有胃泌素和神经元特异性烯醇化酶（NSE）阳性细胞。
