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妊娠滋养细胞疾病诱发的甲状腺风暴

Gestational Trophoblastic Disease-induced Thyroid Storm.

作者信息

Blick Carly, Schreyer Kraftin E

机构信息

Temple University Hospital, Department of Emergency Medicine, Philadelphia, Pennsylvania.

出版信息

Clin Pract Cases Emerg Med. 2019 Oct 21;3(4):409-412. doi: 10.5811/cpcem.2019.9.43656. eCollection 2019 Nov.

DOI:10.5811/cpcem.2019.9.43656
PMID:31763601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6861026/
Abstract

In the United States, gestational trophoblastic diseases (GTD), including molar pregnancies, occur in 121 out of 100,000 pregnancies.1 Many patients with GTD may develop hyperthyroidism. GTD-induced thyroid storm is a rare but life-threatening complication of GTD.2 Once patients are hemodynamically stable, the mainstay of definitive treatment is evacuation of the mole.3 We present a case of molar pregnancy-induced thyroid storm presenting as vaginal bleeding, fever, and tachycardia.

摘要

在美国,每10万例妊娠中有121例发生妊娠滋养细胞疾病(GTD),包括葡萄胎妊娠。许多GTD患者可能会出现甲状腺功能亢进。GTD诱发的甲状腺风暴是GTD一种罕见但危及生命的并发症。一旦患者血流动力学稳定,确定性治疗的主要方法是清除葡萄胎。我们报告一例葡萄胎妊娠诱发甲状腺风暴的病例,表现为阴道出血、发热和心动过速。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2803/6861026/3f8cb06d3c3e/cpcem-03-409-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2803/6861026/3f8cb06d3c3e/cpcem-03-409-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2803/6861026/3f8cb06d3c3e/cpcem-03-409-g001.jpg

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本文引用的文献

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Molar Pregnancy Causing Thyrotoxicosis in a Teenage Girl With Type 1 Diabetes Mellitus.一例患有1型糖尿病的青少年女性因葡萄胎导致甲状腺毒症
Glob Pediatr Health. 2015 Mar 2;2:2333794X15574285. doi: 10.1177/2333794X15574285. eCollection 2015.
2
Thyroid storm-induced multi-organ failure in the setting of gestational trophoblastic disease.妊娠滋养细胞疾病合并甲状腺危象所致多器官功能衰竭
J Emerg Med. 2015 Jan;48(1):35-8. doi: 10.1016/j.jemermed.2014.09.012. Epub 2014 Oct 12.
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Hyperthyroidism and thyrotoxicosis.甲状腺功能亢进症与甲状腺毒症
葡萄胎妊娠所致甲状腺功能亢进:早期识别与及时术前管理的重要性。
JCEM Case Rep. 2023 Dec 6;1(6):luad129. doi: 10.1210/jcemcr/luad129. eCollection 2023 Nov.
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Thyroid. 2011 Jun;21(6):593-646. doi: 10.1089/thy.2010.0417. Epub 2011 Apr 21.
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Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole.妊娠滋养细胞疾病 I:流行病学、病理学、临床表现和诊断、葡萄胎的处理。
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Physiological and pathological aspects of the effect of human chorionic gonadotropin on the thyroid.人绒毛膜促性腺激素对甲状腺影响的生理和病理方面
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