Gao Hong, Liu Dong-E, Li Yumei, Tang Jing, Wu Xinrui, Tan Hongzhuan
School of Nursing, University of South China, Hengyang.
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha.
Medicine (Baltimore). 2019 Nov;98(47):e17966. doi: 10.1097/MD.0000000000017966.
To investigate how uterine size and volume are associated with live birth rate in patients undergoing assisted reproduction technology.This prospective cohort study was conducted at the Reproductive Medicine Centre from January 2010 to May 2017. Multivariate binary logistic regression was used to evaluate the relations between uterine size, total volume, and live birth outcomes, after they were adjusted for the main influencing factors.A total of 7320 women of clinical pregnancy were enrolled. Compared with uterine lengths of 50 to 59 mm (referent), women with uterine lengths ≥60 mm had a lower live birth rate (RR = 1.541). Compared with uterine widths of ≥50 mm (referent), women with uterine widths <30 mm had a lower live birth rate (RR = 1.430). Compared with uterine anteroposterior diameters of <30 mm (referent), women with uterine anteroposterior diameters ≥50 mm had a lower live birth rate (RR = 1.636). Compared with uterine volumes of 30 to 49 mL (referent), women with volumes <30 mL and ≥70 mL had lower live birth rates (RR = 1.368 and 1.742, respectively).Our findings indicate that uterine sizes and volumes that were too large or too small reduced the live birth rate.
研究辅助生殖技术患者的子宫大小和容积与活产率之间的关系。这项前瞻性队列研究于2010年1月至2017年5月在生殖医学中心进行。在对主要影响因素进行校正后，采用多因素二元逻辑回归分析评估子宫大小、总体积与活产结局之间的关系。共纳入7320例临床妊娠女性。与子宫长度为50至59毫米（参照组）的女性相比，子宫长度≥60毫米的女性活产率较低（相对危险度RR = 1.541）。与子宫宽度≥50毫米（参照组）的女性相比，子宫宽度<30毫米的女性活产率较低（RR = 1.430）。与子宫前后径<30毫米（参照组）的女性相比，子宫前后径≥50毫米的女性活产率较低（RR = 1.636）。与子宫容积为30至49毫升（参照组）的女性相比，容积<30毫升和≥70毫升的女性活产率较低（RR分别为1.368和1.742）。我们的研究结果表明，子宫大小和容积过大或过小都会降低活产率。
