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伴有严重血小板减少症的不明子宫颈癌的心脏内转移

Intracardiac metastasis from unknown uterine cervical cancer with severe thrombocytopenia.

作者信息

Kasai Mio, Osako Motohiko, Yamada Toshiyuki, Adachi Masataka, Yamashita Hiroshi, Hatano Mami, Yorozu Atsunori

机构信息

Department of Cardiovascular Surgery, National Hospital Organization Tokyo Medical Center, Japan.

Department of Obsterics and Gynecology, National Hospital Organization Tokyo Medical Center, Japan.

出版信息

J Card Surg. 2020 Feb;35(2):473-476. doi: 10.1111/jocs.14362. Epub 2019 Nov 25.

DOI:10.1111/jocs.14362
PMID:31765009
Abstract

INTRODUCTION

Cardiac metastasis is relatively common in malignant neoplasms, such as lung cancers, breast cancers, melanomas, lymphomas, and leukemias. In contrast, cardiac metastasis of uterine cervical cancer, solitary metastasis to the heart, and tumors inducing severe thrombocytopenia are rare.

CASE REPORT

The present patient was a 52-year-old female who was diagnosed with a solitary cardiac tumor prior to uterine cervical cancer and presented with severe thrombocytopenia. Our case had two remarkable aspects: 1) successful treatment under the condition of severe thrombocytopenia in association with the presence of a cardiac tumor, and survival without recurrence of the carcinoma one year after surgery; and 2) a solitary cardiac metastatic tumor larger than the primary uterine cervix carcinoma.

COMMENT

we report an extremely rare case of solitary cardiac metastasis of uterine cervical cancer, which wassuccessfully treated. One year after cardiac surgery, the patient is alive without recurrence of the carcinoma.

摘要

引言

心脏转移在恶性肿瘤中相对常见,如肺癌、乳腺癌、黑色素瘤、淋巴瘤和白血病。相比之下,子宫颈癌的心脏转移、心脏孤立转移以及导致严重血小板减少的肿瘤较为罕见。

病例报告

本患者为一名52岁女性,在诊断出子宫颈癌之前被诊断出患有心脏孤立肿瘤,并出现严重血小板减少。我们的病例有两个显著特点:1)在严重血小板减少且伴有心脏肿瘤的情况下成功治疗,术后一年癌症无复发存活;2)心脏孤立转移瘤大于原发性子宫颈癌。

评论

我们报告了一例极其罕见的子宫颈癌心脏孤立转移病例,该病例得到了成功治疗。心脏手术后一年,患者存活且癌症无复发。

相似文献

1
Intracardiac metastasis from unknown uterine cervical cancer with severe thrombocytopenia.伴有严重血小板减少症的不明子宫颈癌的心脏内转移
J Card Surg. 2020 Feb;35(2):473-476. doi: 10.1111/jocs.14362. Epub 2019 Nov 25.
2
Isolated right ventricular metastasis of uterine cervical carcinoma.子宫颈癌孤立性右心室转移
Jpn J Thorac Cardiovasc Surg. 2005 Dec;53(12):645-8. doi: 10.1007/BF02665077.
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Isolated cardiac metastasis of cervical carcinoma presenting as disseminated intravascular coagulopathy. A case report.以弥散性血管内凝血为表现的宫颈癌孤立性心脏转移:一例报告
J Reprod Med. 2000 Jul;45(7):603-6.
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Intracardiac metastasis from known cervical cancer: a case report and literature review.心内转移的已知宫颈癌:病例报告及文献复习。
World J Surg Oncol. 2013 May 23;11:107. doi: 10.1186/1477-7819-11-107.
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Cardiac metastasis from carcinoma of the cervix: report of two cases.子宫颈癌的心脏转移:两例报告。
Gynecol Oncol. 1998 Jun;69(3):264-8. doi: 10.1006/gyno.1998.5009.
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Cardiac metastasis from a stage IIIb cervix carcinoma.IIIb期宫颈癌的心脏转移
Acta Cardiol. 2005 Feb;60(1):73-5. doi: 10.2143/AC.60.1.2005055.
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Carcinoma of the uterine cervix with myocardial metastasis.子宫颈癌伴心肌转移
Gynecol Oncol. 1997 Apr;65(1):169-72. doi: 10.1006/gyno.1996.4591.
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[Myocardial metastasis in the right ventricle from uterine cervical carcinoma with high 67Ga-citrate accumulation: a case report].[子宫颈癌右心室心肌转移伴高柠檬酸镓摄取:一例报告]
Kaku Igaku. 1996 Sep;33(9):1011-4.
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Metastatic uterine cervical cell carcinoma to myocardium.转移性子宫颈细胞癌累及心肌。
Clin Nucl Med. 1986 Feb;11(2):131-2. doi: 10.1097/00003072-198602000-00019.
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Right ventricular metastasis of uterine squamous cell carcinoma.子宫鳞状细胞癌的右心室转移
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引用本文的文献

1
Cardiac metastasis in uterine cervical cancer : A systematic review and case study.子宫颈癌的心脏转移:一项系统评价与病例研究
Strahlenther Onkol. 2025 Jan;201(1):71-81. doi: 10.1007/s00066-024-02274-y. Epub 2024 Sep 17.
2
A rare case of cardiac metastasis of squamous cell carcinoma of the cervix with a review of existing case reports and treatment modalities.一例罕见的宫颈鳞状细胞癌心脏转移病例,并对现有病例报告及治疗方式进行综述。
Gynecol Oncol Rep. 2024 Mar 5;52:101352. doi: 10.1016/j.gore.2024.101352. eCollection 2024 Apr.
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Intracavitary cardiac metastasis of cervical squamous cell carcinoma with immune thrombocytopenia: a rare case report.
宫颈鳞状细胞癌伴免疫性血小板减少症的心脏腔内转移:一例罕见病例报告
Front Oncol. 2023 Aug 30;13:1239606. doi: 10.3389/fonc.2023.1239606. eCollection 2023.