Duke Palliative Care, Duke University and Health System, Durham, NC; Department of Medicine, Duke University School of Medicine, Durham, NC; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC.
Department of Medicine, Duke University School of Medicine, Durham, NC; Division of Hematologic Malignancies and Cellular Therapy, Duke University School of Medicine, Durham, NC; Duke Cancer Institute, Durham, NC.
Semin Oncol Nurs. 2019 Dec;35(6):150959. doi: 10.1016/j.soncn.2019.150959. Epub 2019 Nov 22.
To provide an overview of the past, present, and future of the integration of palliative care services for patients with hematologic malignancies, such as acute myeloid leukemia (AML).
Published literature as indexed in Medline, relevant guideline documents, textbooks, and clinical experience.
Patients with acute leukemias have substantial palliative care needs that often go unmet with standard oncology care. Evidence shows that the early integration of specialist palliative care into standard oncology care improves patient-centered outcomes among those with advanced solid tumors. Emerging evidence supports similar benefits among hospitalized patients with hematologic malignancies undergoing stem cell transplantation, and additional trials are underway to further test palliative care interventions in patients with AML.
By better understanding the palliative care needs of patients with AML and the evidence of integration with standard oncologic care, patients with leukemias may be more likely to receive early integrated palliative care.
概述血液系统恶性肿瘤(如急性髓系白血病)患者姑息治疗服务的过去、现在和未来。
Medline 索引的已发表文献、相关指南文件、教科书和临床经验。
急性白血病患者有大量的姑息治疗需求,而这些需求往往无法通过标准肿瘤学治疗得到满足。有证据表明,将专科姑息治疗早期融入标准肿瘤学治疗可以改善晚期实体瘤患者的以患者为中心的治疗结局。新兴证据支持在接受干细胞移植的血液系统恶性肿瘤住院患者中也有类似的益处,并且正在进行更多的试验以进一步测试 AML 患者的姑息治疗干预措施。
通过更好地了解 AML 患者的姑息治疗需求以及姑息治疗与标准肿瘤学治疗相结合的证据,白血病患者可能更有可能接受早期综合姑息治疗。