Karamian A I, Sollertinskaia T N, Ryzhakov M K, Iliukha V A, Siketin V A
Zh Evol Biokhim Fiziol. 1988 May-Jun;24(3):284-94.
In experiments with defensive behaviour, using multiparametric recording of indices, studies have been made on the origin and development of pathological disturbances in the higher nervous activity of insectivores, carnivores and primates during presentation of difficult conditioned reflex problems or extreme stimulation. It was found that elaboration of absolute differentiation retarded conditioned reactions with a delay of 25 s in insectivores is a difficult task which results in pathological changes in the higher nervous activity. In hedgehogs, neurotic changes are immediate, all the investigated indices being affected. In carnivores, especially in primates, the onset of evident pathological changes is preceded by a long preneurotic period, i.e. a stage of self-regulation. In pathological process, more corticalized forms of the nervous activity are initially involved. Common features and differences in the development of pathological changes in the higher nervous activity among mammals are discussed.
在有关防御行为的实验中，通过对各项指标进行多参数记录，研究了食虫动物、食肉动物和灵长类动物在面临困难的条件反射问题或极端刺激时，其高级神经活动中病理紊乱的起源和发展。结果发现，在食虫动物中，建立绝对分化会延迟25秒的条件反应，这是一项艰巨的任务，会导致高级神经活动出现病理变化。在刺猬中，神经症性变化是即时的，所有被研究的指标都会受到影响。在食肉动物中，尤其是灵长类动物，明显的病理变化出现之前会有一个漫长的神经症前期，即自我调节阶段。在病理过程中，神经活动中更具皮层化的形式最初会受到影响。文中讨论了哺乳动物高级神经活动中病理变化发展的共同特征和差异。
