Baumgardner Dennis J
Department of Family Medicine, Aurora UW Medical Group, Aurora Health Care, Milwaukee, WI; Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, Madison, WI; Center for Urban Population Health, Milwaukee, WI.
J Patient Cent Res Rev. 2019 Oct 28;6(4):252-261. doi: 10.17294/2330-0698.1705. eCollection 2019 Fall.
The oral microbiota is complex, multikingdom, interactive, and involves extensive biofilm formation. While dominated by bacteria, is a frequent member of this microbiota; however, several other potentially pathogenic fungi (among around 100 identified species) appear to reside in some individuals, including , and . Oral candidiasis may manifest as a variety of disease entities in normal hosts and in the immunocompromised. These include pseudomembranous candidiasis (thrush), hyperplastic or atrophic (denture) candidiasis, linear gingival erythema, median rhomboid glossitis, and angular cheilitis. The purpose of this review is to describe the oral fungal microbiota (ie, oral mycobiota), common mouth diseases caused by its members, predisposing factors and treatment, and the potential for causing disseminated disease like their bacterial counterparts.
口腔微生物群复杂、多界、相互作用,且涉及广泛的生物膜形成。虽然以细菌为主导,但真菌也是该微生物群的常见成员;然而,其他几种潜在致病真菌(在已鉴定的约100种物种中)似乎存在于一些个体中,包括白色念珠菌、热带念珠菌和近平滑念珠菌。口腔念珠菌病在正常宿主和免疫功能低下者中可能表现为多种疾病形式。这些包括假膜性念珠菌病(鹅口疮)、增生性或萎缩性(义齿)念珠菌病、线性牙龈红斑、正中菱形舌炎和口角炎。本综述的目的是描述口腔真菌微生物群(即口腔真菌群)、其成员引起的常见口腔疾病、易感因素和治疗方法,以及像其细菌对应物一样引起播散性疾病的可能性。