HIV 中的真菌组。
The mycobiome in HIV.
机构信息
Center for Medical Mycology, Case Western Reserve University, and University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
出版信息
Curr Opin HIV AIDS. 2018 Jan;13(1):69-72. doi: 10.1097/COH.0000000000000432.
PURPOSE OF REVIEW
There are a limited number of studies investigating the association between the microbiome and HIV. Although the majority of these published investigations have focused on the role of the bacterial community (bacteriome) in this setting, a handful of studies have also characterized the role of the mycobiome in HIV-infected individuals. This review will summarize the most recent reports pertaining to the role of the fungal community in HIV.
RECENT FINDINGS
Differences in the composition of the oral and respiratory mycobiome in HIV-infected individuals compared with uninfected individuals have been reported.
SUMMARY
Our review shows that studies investigating the role of the mycobiome in the setting of HIV are severely lacking. With recent advances in our understanding of the composition of the human microbiome, investigations into the role of the bacteria and fungus comprising the overall microbiota and how the two interact to influence each other and the host is crucial.
目的综述
目前，有关微生物组与 HIV 之间关联的研究数量有限。尽管大多数已发表的研究都集中在细菌群落（细菌组）在这一环境中的作用，但少数研究也描述了真菌组在 HIV 感染者中的作用。本综述将总结与 HIV 相关的真菌群落作用的最新报告。
最近的发现
与未感染个体相比，HIV 感染者的口腔和呼吸道真菌群落组成存在差异。
总结
我们的综述表明，目前在 HIV 环境中研究真菌组作用的研究严重不足。随着我们对人类微生物组组成的理解不断深入，研究细菌和真菌组成的整体微生物组的作用以及两者如何相互作用以影响彼此和宿主至关重要。
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