Poutiainen E, Iivanainen M, Elovaara I, Valle S L, Lähdevirta J
Department of Neurology, University Central Hospital, Helsinki, Finland.
Acta Neurol Scand. 1988 Jul;78(1):49-52. doi: 10.1111/j.1600-0404.1988.tb03618.x.
Neuropsychological examination was performed on 13 patients and 10 matched controls to assess the brain involvement of patients with human immunodeficiency virus (HIV) infection. HIV-infected patients showed a significant decline in visuomotor, visuoconstructive and practical abilities as well as in motor-free visuospatial performance and repeating a long sentence. These findings could not be explained by the concomitant mental depression of these patients. Neither were they associated with any particular stage of HIV infection. The results suggest that mild cognitive changes may be detected even in the early stages of HIV infection, when examined by appropriate neuropsychological methods.
对13例患者和10例匹配的对照者进行了神经心理学检查，以评估人类免疫缺陷病毒（HIV）感染患者的脑受累情况。HIV感染患者在视运动、视构建和实践能力以及无运动的视觉空间表现和复述长句方面均出现显著下降。这些发现无法用这些患者同时存在的精神抑郁来解释。它们也与HIV感染的任何特定阶段无关。结果表明，当采用适当的神经心理学方法进行检查时，即使在HIV感染的早期阶段也可能检测到轻度认知变化。
