Suppr超能文献

经皮内窥镜腰椎间盘切除术治疗伴有 Modic 改变的腰椎间盘突出症:一项回顾性研究。

Percutaneous Endoscopic Lumbar Discectomy for Lumbar Disc Herniation with Modic Changes via a Transforaminal Approach: A Retrospective Study.

机构信息

Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

出版信息

Pain Physician. 2019 Nov;22(6):E601-E608.

Abstract

BACKGROUND

The surgical selection for patients with lumbar disc herniation (LDH) with Modic changes (MCs) is still contentious. Percutaneous endoscopic lumbar discectomy via a transforaminal approach (TF-PELD) as a representative minimally invasive spine surgery technique for LDH has been standardized. However, its efficacy has not been thoroughly described in the patients with LDH with MCs.

OBJECTIVES

The goal of this study was to assess the clinical outcomes of TF-PELD in the treatment of LDH and MCs.

STUDY DESIGN

Retrospective study.

SETTING

Inpatient surgery center.

METHODS

From January 2015 to December 2016, 276 patients with LDH showing normal or MCs signals in their bone marrow in our hospital were enrolled in this retrospective study. All patients suffered low back and leg pain because of LDH and underwent the TF-PELD procedure. Clinical outcomes were assessed according to the Visual Analog Scale (VAS) for back pain and leg pain, Oswestry Disability Index (ODI) for functional status assessment, and modified MacNab criteria for patient satisfaction.

RESULTS

A total of 182 patients showed normal intensity, 44 patients showed Modic type 1 signals, and 50 patients showed Modic type 2 signals before surgery. The postoperative VAS and ODI scores were significantly improved compared with those preoperatively among the groups. In the Modic type 1 and 2 signals groups, however, the postoperative VAS scores for back pain and ODI scores showed an upward trend with the follow-up time extending. The recurrence rates were 4.4%, 9.1%, and 8.0% in the normal, Modic type 1 and 2 signals groups, respectively. The recurrence rates and satisfaction rates showed no significant difference among the groups at the final follow-up.

LIMITATIONS

This study has a small sample size and the follow-up period was too short. There is no comparison with other therapeutic options such as fusion surgery or the lack of any other treatment.

CONCLUSIONS

TF-PELD is an option for treatment of patients with LDH even if the patients show MCs. However, the postoperative back pain and functional status have the trend of deterioration with the time extending in patients with MCs, especially in the Modic type 1 signals.

KEY WORDS

Modic changes, Modic type 1, Modic type 2, transforaminal percutaneous endoscopic lumbar discectomy, lumbar disc herniation, back pain, recurrence, complication.

摘要

背景

对于伴有 Modic 改变(MCs)的腰椎间盘突出症(LDH)患者的手术选择仍存在争议。经皮经椎间孔内窥镜腰椎间盘切除术(TF-PELD)作为 LDH 的一种代表性微创脊柱手术技术已经标准化。然而,其在伴有 MCs 的 LDH 患者中的疗效尚未得到充分描述。

目的

本研究旨在评估 TF-PELD 治疗 LDH 和 MCs 的临床疗效。

研究设计

回顾性研究。

设置

住院手术中心。

方法

自 2015 年 1 月至 2016 年 12 月,我院收治了 276 例 LDH 患者,这些患者的骨髓中均显示正常或 MCs 信号。所有患者均因 LDH 而遭受腰痛和腿痛,并接受了 TF-PELD 手术。根据腰痛和腿痛的视觉模拟评分(VAS)、功能状态的 Oswestry 残疾指数(ODI)以及改良 MacNab 标准评估患者满意度来评估临床疗效。

结果

术前,共有 182 例患者表现为正常强度,44 例患者表现为 Modic 1 型信号,50 例患者表现为 Modic 2 型信号。与术前相比,各组术后 VAS 和 ODI 评分均显著改善。然而,在 Modic 1 型和 2 型信号组中,随着随访时间的延长,术后腰痛 VAS 评分和 ODI 评分呈上升趋势。在正常、Modic 1 型和 2 型信号组中,复发率分别为 4.4%、9.1%和 8.0%。在最后一次随访时,各组之间的复发率和满意度没有显著差异。

局限性

本研究样本量较小,随访时间过短。没有与融合手术等其他治疗方法进行比较,也没有其他治疗方法的比较。

结论

即使患者出现 MCs,TF-PELD 也是治疗 LDH 患者的一种选择。然而,在 MCs 患者中,随着时间的延长,术后腰痛和功能状态有恶化的趋势,尤其是在 Modic 1 型信号患者中。

关键词

Modic 改变;Modic 1 型;Modic 2 型;经皮经椎间孔内窥镜腰椎间盘切除术;腰椎间盘突出症;腰痛;复发;并发症。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验