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经皮内镜下腰椎间盘切除术治疗伴有 II 型 Modic 改变的腰椎间盘突出症。

Percutaneous Endoscopic Lumbar Discectomy for Lumbar Disc Herniation With Type II Modic Changes.

机构信息

Department of Orthopedic Surgery, The Affiliated Huaian First People's Hospital of Nanjing Medical University, Huaian, China.

Department of Orthopedic Surgery, The Affiliated Hospital of Yangzhou University, Yangzhou, China.

出版信息

World Neurosurg. 2022 Aug;164:e143-e149. doi: 10.1016/j.wneu.2022.04.056. Epub 2022 Apr 28.

Abstract

BACKGROUND

Percutaneous endoscopic lumbar discectomy (PELD) has become a favorable surgical approach for lumbar radiculopathy caused by intervertebral disc herniation. Studies have revealed patients with type II Modic change may suffer from unrelieved low back pain and higher lumbar disc herniation (LDH) recurrence after herniated nucleus pulposus removal. Therefore, in this study, we aim to evaluate how PELD performed in management of LDH patients with type II Modic change.

METHODS

We collected 267 single-level LDH cases aged 20-50 yearswho underwent PELD from December 2016 to December 2019. The mean follow-up time was 26.3 months (range: 12-48 months). The visual analog scale (VAS), Oswestry Disability Index (ODI), and MacNab scores, as well as the recurrence rate, were analyzed pre- and post-surgery, as well as at the time points of 3 months, 12 months, and the final follow-up time after surgery. The clinical outcomes in LDH patients with or without type II Modic change who underwent PELD were thoroughly analyzed.

RESULTS

Within the 267 LDH patients enrolled, 145 cases present Modic signals, among which 3 are type I and 142 are type II. The VAS and ODI scores of the patients in the 2 groups at different follow-up times were significantly lower than those before surgery. The excellent and good MacNab scores in the control group and Modic type II change group were 87.0% and 82.1%, respectively. However, with the extension of follow-up time, the VAS and ODI scores, as well as the recurrence rate, were found to be higher in the type II Modic change group when compared with those in the non-Modic change group.

CONCLUSIONS

PELD performed well in management of LDH patients. However, we need to pay more attention to the continuous low back pain and the recurrence possibility in the cases with type II Modic change. In these cases, longer brace support or other interventions could be applied.

摘要

背景

经皮内镜腰椎间盘切除术(PELD)已成为治疗椎间盘突出症引起的腰椎神经根病的一种有利的手术方法。研究表明,II 型 Modic 改变的患者在去除突出的髓核后可能会遭受持续的腰痛和更高的腰椎间盘突出症(LDH)复发率。因此,在本研究中,我们旨在评估 PELD 治疗 II 型 Modic 改变的 LDH 患者的效果。

方法

我们收集了 2016 年 12 月至 2019 年 12 月期间接受 PELD 治疗的 267 例单节段 LDH 患者。平均随访时间为 26.3 个月(范围:12-48 个月)。分析术前、术后以及术后 3 个月、12 个月和最终随访时间的视觉模拟评分(VAS)、Oswestry 功能障碍指数(ODI)和 MacNab 评分,以及复发率。彻底分析了接受 PELD 治疗的 LDH 患者是否存在 II 型 Modic 改变的临床结果。

结果

在纳入的 267 例 LDH 患者中,145 例存在 Modic 信号,其中 3 例为 I 型,142 例为 II 型。两组患者在不同随访时间的 VAS 和 ODI 评分均明显低于术前。对照组和 Modic II 型改变组的优秀和良好 MacNab 评分分别为 87.0%和 82.1%。然而,随着随访时间的延长,II 型 Modic 改变组的 VAS 和 ODI 评分以及复发率均高于非 Modic 改变组。

结论

PELD 治疗 LDH 患者效果良好。然而,我们需要更加关注 II 型 Modic 改变患者持续腰痛和复发的可能性。在这些情况下,可以应用更长时间的支具支持或其他干预措施。

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