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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Schnabel I, Fricke H J, Jansa U, Lehmann G

Z Gesamte Inn Med. 1979 Dec 1;34(23):704-8.

In non-Hodgkin-lymphomas with leucaemic form of the course a significant percental decrease of the number of T-lymphocytes and an also significant increase of the number of B-lymphocytes was to be proved. The increase of the B-lymphocytes concerned among others cells which carry the ME-receptor. 2. In non-Hodgkin-lymphomas with aleucaemic form of the course in decrease of the absolute number of lymphocytes a relative and absolute increase of the subpopulation of lymphocytes carrying the ME-receptor was provable. 3. In the course control of 7 patients with non-Hodgkin-lymphoma under polychemotherapy in 5 cases a discrepancy between the number of rosette-forming cells and the total number of lymphocytes appeared. 4. In the monotherapy of patients with CLL in favourable clinical development a percental increase of the T-cells is objectifiable after one year. A similar development was to be found in 3 patients after the first cycle with CVP.

在病程呈白血病样的非霍奇金淋巴瘤中，T淋巴细胞数量显著减少，B淋巴细胞数量也显著增加。B淋巴细胞的增加涉及携带ME受体的其他细胞。2. 在病程呈无白血病样的非霍奇金淋巴瘤中，淋巴细胞绝对数量减少，携带ME受体的淋巴细胞亚群相对及绝对数量增加是可证实的。3. 在7例接受多药化疗的非霍奇金淋巴瘤患者的病程对照中，5例出现玫瑰花结形成细胞数量与淋巴细胞总数之间的差异。4. 在慢性淋巴细胞白血病患者的单药治疗中，临床进展良好的情况下，一年后T细胞百分比增加是可观察到的。在3例接受CVP首个疗程治疗后的患者中也发现了类似情况。

Schnabel I, Fricke H J, Jansa U, Lehmann G

Z Gesamte Inn Med. 1979 Dec 1;34(23):704-8.

In non-Hodgkin-lymphomas with leucaemic form of the course a significant percental decrease of the number of T-lymphocytes and an also significant increase of the number of B-lymphocytes was to be proved. The increase of the B-lymphocytes concerned among others cells which carry the ME-receptor. 2. In non-Hodgkin-lymphomas with aleucaemic form of the course in decrease of the absolute number of lymphocytes a relative and absolute increase of the subpopulation of lymphocytes carrying the ME-receptor was provable. 3. In the course control of 7 patients with non-Hodgkin-lymphoma under polychemotherapy in 5 cases a discrepancy between the number of rosette-forming cells and the total number of lymphocytes appeared. 4. In the monotherapy of patients with CLL in favourable clinical development a percental increase of the T-cells is objectifiable after one year. A similar development was to be found in 3 patients after the first cycle with CVP.

在病程呈白血病样的非霍奇金淋巴瘤中，T淋巴细胞数量显著减少，B淋巴细胞数量也显著增加。B淋巴细胞的增加涉及携带ME受体的其他细胞。2. 在病程呈无白血病样的非霍奇金淋巴瘤中，淋巴细胞绝对数量减少，携带ME受体的淋巴细胞亚群相对及绝对数量增加是可证实的。3. 在7例接受多药化疗的非霍奇金淋巴瘤患者的病程对照中，5例出现玫瑰花结形成细胞数量与淋巴细胞总数之间的差异。4. 在慢性淋巴细胞白血病患者的单药治疗中，临床进展良好的情况下，一年后T细胞百分比增加是可观察到的。在3例接受CVP首个疗程治疗后的患者中也发现了类似情况。