Division of Gastroenterology and Hepatology, Department of Medicine, University of California - San Francisco, San Francisco, California.
Division of Gastroenterology and Hepatology, Department of Medicine, California Pacific Medical Center, San Francisco, California.
Neurogastroenterol Motil. 2020 Mar;32(3). doi: 10.1111/nmo.13761. Epub 2019 Nov 27.
Epiphrenic (pulsion) esophageal diverticula can occur in the setting of underlying esophageal motility disorders such as achalasia and present a unique management challenge to the gastroenterologist. Asymptomatic diverticula do not require treatment, but symptomatic diverticula require therapy targeted to the underlying esophageal motility disorder, or else the diverticula will recur. Generally, laparoscopic or combined laparoscopic/thoracoscopic myotomy, diverticulectomy, and anterior fundoplication are required. However, therapeutic options for epiphrenic diverticula are evolving as peroral endoscopic myotomy (POEM) becomes more commonplace. We review two cases of achalasia complicated by epiphrenic diverticula at our institution. In the first case, type II achalasia was identified and the patient underwent laparoscopic myotomy. In the second case, type III achalasia was present and the patient underwent successful POEM. We discuss the presentation, pathophysiology, and management of epiphrenic diverticula as well as the expanding role for POEM in diverticula.
膈上(推动性)食管憩室可发生于食管动力障碍性疾病(如贲门失弛缓症)患者,给胃肠病医生带来独特的治疗挑战。无症状的憩室无需治疗,但有症状的憩室需要针对潜在的食管动力障碍进行治疗,否则憩室会复发。通常,需要腹腔镜或联合腹腔镜/胸腔镜肌切开术、憩室切除术和前位胃底折叠术。然而,随着经口内镜肌切开术(POEM)变得越来越普遍,膈上憩室的治疗选择也在不断发展。我们回顾了在我们机构发生的两例贲门失弛缓症合并膈上憩室的病例。在第一个病例中,诊断为 II 型贲门失弛缓症,患者接受了腹腔镜肌切开术。在第二个病例中,存在 III 型贲门失弛缓症,患者成功接受了 POEM。我们讨论了膈上憩室的表现、病理生理学和治疗,以及 POEM 在憩室治疗中的扩展作用。