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膈食管裂孔疝与非裂孔疝食管动力障碍的 Heller 肌切开术比较:单中心经验及患者特征、高分辨率测压和结局评估。

Heller Myotomy for Epiphrenic Diverticula Compared to Nondiverticula Esophageal Motility Disorders, A Single Institution Experience and Appraisal of Patient Characteristics, High-Resolution Manometry and Outcomes.

机构信息

Division of General Surgery, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.

Division of Gastroenterology, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.

出版信息

Dig Surg. 2020;37(1):72-80. doi: 10.1159/000496804. Epub 2019 Feb 5.

Abstract

PURPOSE

The purpose of this study was to compare demographics, symptoms, prior interventions, operation, and outcomes of patients who underwent Heller myotomy for esophageal motility disorders and epiphrenic diverticulectomy with Heller myotomy.

METHODS

We identified all patients who underwent Heller myotomy for esophageal motility disorders with and without esophageal diverticulectomy over an 80-month period. Primary data points included patient demographics, presenting symptoms, prior intervention, high-resolution manometry, surgery performed with rate of laparoscopic, conversion to open, and open procedures; postoperative complications, and symptom resolution.

RESULTS

Over the study period, 308 Heller esophagomyotomy operations were performed on 301 patients. Of these, 277 cases were without epiphrenic diverticula and 31 included diverticula. One patient with an asymptomatic epiphrenic diverticulum did not undergo surgery was included, for a total of 32 diverticula patients. Six patients in the non-diverticula group and 1 in the diverticula group required a second operation for recurrent symptoms or residual diverticulum. The diverticula group was significantly older, had different manometry findings, required more open operations, and had longer length of stay. The diverticula group had a lower frequency of patients with prior interventions, but similar postoperative leaks, higher overall postoperative complications, and no difference in reported symptomatic improvement.

CONCLUSIONS

Esophageal diverticula patients have a unique profile compare to patients with non-diverticula motility disorders. Operations are more complex, with increased complication rate and a longer length of stay. In spite of this, there is no statistically significant difference in symptomatic outcomes between the groups.

摘要

目的

本研究旨在比较行食管动力障碍 Heller 肌切开术和 Heller 肌切开术合并膈食管憩室切除术的患者的人口统计学、症状、既往干预措施、手术和结局。

方法

我们确定了 80 个月内所有接受 Heller 肌切开术治疗食管动力障碍伴或不伴食管憩室的患者。主要数据点包括患者人口统计学、临床表现、既往干预、高分辨率测压、手术方式(腹腔镜、转为开腹和开腹手术)、术后并发症和症状缓解情况。

结果

在研究期间,对 301 名患者中的 308 例 Heller 食管肌切开术进行了手术。其中,277 例无膈食管憩室,31 例包括憩室。一名无症状膈食管憩室患者未接受手术,共 32 例憩室患者。非憩室组中有 6 例和憩室组中有 1 例因症状复发或残留憩室需要再次手术。憩室组患者年龄较大,测压结果不同,需要更多的开腹手术,住院时间更长。憩室组患者既往干预的比例较低,但术后漏诊率较高,总术后并发症发生率较高,报告的症状改善无差异。

结论

与非憩室动力障碍患者相比,食管憩室患者具有独特的特征。手术更为复杂,并发症发生率更高,住院时间更长。尽管如此,两组患者的症状改善结果并无统计学差异。

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