Westcott Carl J, O'Connor Sean, Preiss Joshua E, Patti Marco G, Farrell Timothy M
1 Department of Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
2 Department of Surgery, The W.G. Hefner Veterans Medical Center, Salisbury, North Carolina.
J Laparoendosc Adv Surg Tech A. 2019 Jun;29(6):726-729. doi: 10.1089/lap.2019.0239. Epub 2019 Apr 29.
Epiphrenic esophageal diverticula are typically treated with concurrent cardiomyotomy and diverticulectomy. However, resection of these diverticula can be technically difficult and associated with significant morbidity with a staple line leak rate ranging up to 27%. For this reason, and because the diverticulum is secondary to a primary esophageal motility disorder such as achalasia, we decided to adopt a laparoscopic myotomy-first strategy, reserving the diverticulectomy for patients with persistent or recurrent symptoms. From 2004 to 2018, 22 patients with epiphrenic diverticula were treated by laparoscopic Heller myotomy and partial fundoplication alone, with the plan to add the diverticulectomy as a second stage if needed. There were 13 women and 9 women, with a mean age of 68 years. Patients had been symptomatic for an average of 36 months. The most common presenting symptom was dysphagia (91%), followed by regurgitation (77%). More than half of the diverticula were solitary and on the right side. Esogphagoscopy ruled out cancer. Esophageal manometry (18 patients) showed achalasia in 14 patients, nutcracker esophagus in 3 patients, and nonspecific motility disorder in 1 patient. There were no perioperative complications, and average length of stay was 2.5 days. At a mean follow-up of 68 months, dysphagia resolved in 77% and regurgitation in 86% of patients. Three patients had persistent symptoms: 2 patients underwent a transthoracic diverticulectomy (1 patient with resolution of symptoms and 1 patient with no improvement). Another patient had per oral endoscopic myotomy, but his dysphagia persisted. The laparoscopic myotomy-first approach reduces risk and unnecessary surgery. A laparoscopic Heller myotomy and partial fundoplication provide excellent resolution of symptoms for most, whereasonly a few will need a staged resection of the diverticulum.
膈上型食管憩室通常采用同时进行贲门肌切开术和憩室切除术治疗。然而,切除这些憩室在技术上可能具有挑战性,且并发症发生率较高,吻合口漏发生率高达27%。因此,鉴于憩室继发于诸如贲门失弛缓症等原发性食管动力障碍,我们决定采用腹腔镜下先进行肌切开术的策略,对于症状持续或复发的患者再行憩室切除术。2004年至2018年期间,22例膈上型憩室患者接受了单纯腹腔镜下Heller肌切开术和部分胃底折叠术治疗,并计划在必要时二期行憩室切除术。其中女性13例,男性9例,平均年龄68岁。患者出现症状的平均时间为36个月。最常见的症状是吞咽困难(91%),其次是反流(77%)。超过一半的憩室为单发且位于右侧。食管镜检查排除了癌症。食管测压(18例患者)显示,14例患者为贲门失弛缓症,3例患者为胡桃夹食管,1例患者为非特异性动力障碍。围手术期无并发症发生,平均住院时间为2.5天。平均随访68个月时,77%的患者吞咽困难症状缓解,86%的患者反流症状缓解。3例患者症状持续存在:2例患者接受了开胸憩室切除术(1例症状缓解,1例无改善)。另1例患者接受了经口内镜下肌切开术,但其吞咽困难症状仍持续存在。腹腔镜下先进行肌切开术的方法降低了风险和不必要的手术。腹腔镜下Heller肌切开术和部分胃底折叠术可使大多数患者症状得到良好缓解,只有少数患者需要分期切除憩室。