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台湾绦虫病研究。五、甲苯达唑和吡喹酮治疗绦虫病疗效评估的现场试验。

Studies on taeniasis in Taiwan. V. Field trial on evaluation of therapeutic efficacy of mebendazole and praziquantel against taeniasis.

作者信息

Fan P C, Chung W C, Chan C H, Chen Y A, Cheng F Y, Hsu M C

出版信息

Southeast Asian J Trop Med Public Health. 1986 Mar;17(1):82-90.

PMID:3738612
Abstract

Taeniasis is a major public health problem among the aboriginal populations on Taiwan, and is highly prevalent and wide spread in the mountain areas of 10 Counties. Over 27,000 cases of tapeworm infection are estimated influencing the health and economy in the endemic areas. A treatment of taeniasis with mebendazole and praziquantel followed by a re-treatment with atabrine has been done in the field trial, and confirmed that praziquantel is highly effective agent against tapeworm infection, but mebendazole is not. Based upon experiments reported here praziquantel in a single dose of 150 mg, and 450 mg are highly effective against taeniasis and hymenolepiasis respectively.

摘要

绦虫病是台湾原住民中的一个主要公共卫生问题,在10个县的山区高度流行且广泛传播。据估计,超过27000例绦虫感染病例影响着流行地区的健康和经济。在现场试验中,已采用甲苯咪唑和吡喹酮治疗绦虫病,随后再用阿的平进行复治,结果证实吡喹酮是治疗绦虫感染的高效药物,但甲苯咪唑并非如此。根据此处报道的实验,单剂量150毫克的吡喹酮对绦虫病高效,单剂量450毫克的吡喹酮对膜壳绦虫病高效。

相似文献

1
Studies on taeniasis in Taiwan. V. Field trial on evaluation of therapeutic efficacy of mebendazole and praziquantel against taeniasis.台湾绦虫病研究。五、甲苯达唑和吡喹酮治疗绦虫病疗效评估的现场试验。
Southeast Asian J Trop Med Public Health. 1986 Mar;17(1):82-90.
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Treatment of taeniasis and hymenolepiasis nana with a single oral dose of praziquantel. Study of therapeutic efficacy, tolerance and safety.单剂量口服吡喹酮治疗绦虫病和微小膜壳绦虫病。治疗效果、耐受性和安全性研究。
Mater Med Pol. 1984 Apr-Dec;16(2-4):129-33.
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The use of mebendazole in the treatment of Taenia saginata taeniasis in an endemic area in the Philippines.在菲律宾某流行地区使用甲苯达唑治疗牛带绦虫病。
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[An analysis of the results of clinical trials of praziquantel analogs in intestinal cestode and trematode infections. 1. The treatment of intestinal cestode infections (diphyllobothriasis, taeniasis, hymenolepiasis)].吡喹酮类似物治疗肠道绦虫和吸虫感染的临床试验结果分析。1. 肠道绦虫感染(阔节裂头绦虫病、带绦虫病、微小膜壳绦虫病)的治疗
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Studies on efficacy of praziquantel and mebendazole-medicated salt in treatment of Echinochasmus fujianensis infection.吡喹酮和甲苯咪唑药盐治疗福建棘隙吸虫感染的疗效研究。
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[Therapeutic of taeniasis and hymenolepiasis nana with single oral dose of praziquantel. Study of the efficacy, tolerance and safety].
Rev Inst Med Trop Sao Paulo. 1980 Mar-Apr;22(2):82-8.

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