Fan P C, Chung W C, Chan C H, Chen Y A, Cheng F Y, Hsu M C
Southeast Asian J Trop Med Public Health. 1986 Mar;17(1):82-90.
Taeniasis is a major public health problem among the aboriginal populations on Taiwan, and is highly prevalent and wide spread in the mountain areas of 10 Counties. Over 27,000 cases of tapeworm infection are estimated influencing the health and economy in the endemic areas. A treatment of taeniasis with mebendazole and praziquantel followed by a re-treatment with atabrine has been done in the field trial, and confirmed that praziquantel is highly effective agent against tapeworm infection, but mebendazole is not. Based upon experiments reported here praziquantel in a single dose of 150 mg, and 450 mg are highly effective against taeniasis and hymenolepiasis respectively.
绦虫病是台湾原住民中的一个主要公共卫生问题,在10个县的山区高度流行且广泛传播。据估计,超过27000例绦虫感染病例影响着流行地区的健康和经济。在现场试验中,已采用甲苯咪唑和吡喹酮治疗绦虫病,随后再用阿的平进行复治,结果证实吡喹酮是治疗绦虫感染的高效药物,但甲苯咪唑并非如此。根据此处报道的实验,单剂量150毫克的吡喹酮对绦虫病高效,单剂量450毫克的吡喹酮对膜壳绦虫病高效。