Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, Beijing 100191, China.
Chinese Academy for Environmental Planning, Beijing 100012, China.
J Environ Sci (China). 2019 Dec;86:154-163. doi: 10.1016/j.jes.2019.05.015. Epub 2019 May 22.
Previous studies have reported associations of short-term exposure to different sources of ambient fine particulate matter (PM) and increased mortality or hospitalizations for respiratory diseases. Few studies, however, have focused on the short-term effects of source-specific PM on emergency room visits (ERVs) of respiratory diseases. Source apportionment for PM was performed with Positive Matrix Factorization (PMF) and generalized additive model was applied to estimate associations between source-specific PM and respiratory disease ERVs. The association of PM and total respiratory ERVs was found on lag4 (RR = 1.011, 95%CI: 1.002, 1.020) per interquartile range (76 μg/m) increase. We found PM to be significantly associated with asthma, bronchitis and chronic obstructive pulmonary disease (COPD) ERVs, with the strongest effects on lag5 (RR = 1.072, 95%CI: 1.024, 1.119), lag4 (RR = 1.104, 95%CI: 1.032, 1.176) and lag3 (RR = 1.091, 95%CI: 1.047, 1.135), respectively. The estimated effects of PM changed little after adjusting for different air pollutants. Six primary PM sources were identified using PMF analysis, including dust/soil (6.7%), industry emission (4.5%), secondary aerosols (30.3%), metal processing (3.2%), coal combustion (37.5%) and traffic-related source (17.8%). Some of the sources were identified to have effects on ERVs of total respiratory diseases (dust/soil, secondary aerosols, metal processing, coal combustion and traffic-related source), bronchitis ERVs (dust/soil) and COPD ERVs (traffic-related source, industry emission and secondary aerosols). Different sources of PM contribute to increased risk of respiratory ERVs to different extents, which may provide potential implications for the decision making of air quality related policies, rational emission control and public health welfare.
先前的研究报告称,短期暴露于不同来源的环境细颗粒物 (PM) 与呼吸疾病的死亡率或住院率增加有关。然而,很少有研究关注特定来源的 PM 对呼吸疾病急诊室就诊 (ERV) 的短期影响。使用正定矩阵因子分解 (PMF) 进行 PM 源分配,并应用广义加性模型来估计特定来源的 PM 与呼吸疾病 ERV 之间的关联。研究发现,在第 4 天滞后 (RR=1.011,95%CI:1.002,1.020),每增加一个四分位距 (76μg/m),PM 与总呼吸 ERV 之间存在关联。我们发现 PM 与哮喘、支气管炎和慢性阻塞性肺疾病 (COPD) ERV 显著相关,在第 5 天滞后 (RR=1.072,95%CI:1.024,1.119)、第 4 天滞后 (RR=1.104,95%CI:1.032,1.176) 和第 3 天滞后 (RR=1.091,95%CI:1.047,1.135) 的影响最强。调整不同空气污染物后,PM 的估计影响变化不大。使用 PMF 分析确定了六个主要的 PM 源,包括灰尘/土壤 (6.7%)、工业排放 (4.5%)、二次气溶胶 (30.3%)、金属加工 (3.2%)、煤燃烧 (37.5%)和交通相关源 (17.8%)。一些来源被确定对总呼吸疾病 ERV (灰尘/土壤、二次气溶胶、金属加工、煤燃烧和交通相关源)、支气管炎 ERV (灰尘/土壤) 和 COPD ERV (交通相关源、工业排放和二次气溶胶) 有影响。不同来源的 PM 对呼吸 ERV 的增加风险的贡献程度不同,这可能为空气质量相关政策的决策、合理的排放控制和公共卫生福利提供潜在的启示。