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中国北京,细颗粒物急性暴露与心血管医院急诊就诊。

Acute exposure to fine particulate matter and cardiovascular hospital emergency room visits in Beijing, China.

机构信息

School of Public Health, Capital Medical University, Beijing, China; Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.

Beijing Chao-yang Hospital, Capital Medical University, Beijing, China.

出版信息

Environ Pollut. 2017 Jan;220(Pt A):317-327. doi: 10.1016/j.envpol.2016.09.065. Epub 2016 Sep 30.

Abstract

Fine particulate matter (PM) air pollution outbreaks have recently occurred frequently in China. However, evidence of the associations between short-term exposure to PM and cardiovascular morbidity is still limited in China. This study aimed to evaluate the associations between PM and hospital emergency room visits (ERVs) for cardiovascular diseases in urban areas in Beijing. Daily counts of cardiovascular ERVs were collected from ten large general hospitals from Jan 1 to Dec 31, 2013. Air pollution data were obtained from the Beijing Environmental Protection Bureau including 17 monitoring stations. A generalized additive Poisson model was used to examine the associations between PM and cardiovascular ERVs after controlling for seasonality, day of the week, public holidays, influenza outbreaks, and weather conditions. In total, there were 56,221 cardiovascular ERVs during the study period. The daily mean PM concentration was 102.1 μg/m, ranging from 6.7 μg/m to 508.5 μg/m. Per 10 μg/m increase in PM was associated with a 0.14% (95% confidence interval [CI]: 0.01%-0.27%) increase in cardiovascular ERVs at lag. Cumulative delayed estimates were greatest at lag (0.30%, 95% CI: 0.09%-0.52%). The estimates of percentage change in daily ERVs per 10 μg/m increase in PM were 0.56% (95%CI: 0.16%-0.95%) for ischemic heart disease (IHD) at lag, 0.81% (95%CI: 0.05%-1.57%) for heart rhythm disturbances (HRD) at lag and 1.21% (95%CI: 0.27%-2.15%) for heart failure (HF) at lag, respectively. The effects of PM on IHD ERVs during high temperature days (>11.01 °C) were significantly higher than that on low temperature days (≤11.01 °C) at lag, lag, lag and lag (P < 0.05). The study suggests that PM has acute impacts on cardiovascular ERVs in Beijing, especially on IHD, HRD and HF. The effects of PM on IHD ERVs vary by temperature.

摘要

细颗粒物(PM)空气污染爆发最近在中国频繁发生。然而,在中国,关于短期暴露于 PM 与心血管发病率之间关联的证据仍然有限。本研究旨在评估北京市城区 PM 与心血管疾病急诊室就诊(ERVs)之间的关联。2013 年 1 月 1 日至 12 月 31 日,从 10 家大型综合医院收集每日心血管 ERV 计数。空气污染数据来自北京市环境保护局,包括 17 个监测站。在控制季节性、星期几、公共假日、流感爆发和天气条件后,使用广义加性泊松模型检查 PM 与心血管 ERV 之间的关联。在研究期间,共有 56221 例心血管 ERV。每日平均 PM 浓度为 102.1μg/m,范围为 6.7μg/m 至 508.5μg/m。PM 每增加 10μg/m,心血管 ERV 增加 0.14%(95%置信区间 [CI]:0.01%-0.27%)。滞后时累积延迟估计值最大。PM 每增加 10μg/m,每日 ERV 增加的百分比变化估计值分别为滞后时缺血性心脏病(IHD)为 0.56%(95%CI:0.16%-0.95%)、滞后时心律失常(HRD)为 0.81%(95%CI:0.05%-1.57%)和滞后时心力衰竭(HF)为 1.21%(95%CI:0.27%-2.15%)。PM 对高温日(>11.01°C)IHD ERV 的影响明显高于低温日(≤11.01°C),在滞后、滞后、滞后和滞后时(P<0.05)。该研究表明,PM 对北京心血管 ERV 有急性影响,尤其是对 IHD、HRD 和 HF。PM 对 IHD ERV 的影响因温度而异。

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