新型全氟化合物乳剂的生物相容性研究
Biocompatibility studies with a novel perfluorochemical emulsion.
作者信息
Bollands A D, Lowe K C, Sharma S K, Davis S S
机构信息
Department of Zoology, University of Nottingham, U.K.
出版信息
Biomater Artif Cells Artif Organs. 1988;16(1-3):451-3. doi: 10.3109/10731198809132598.
Biocompatibility studies with a novel perfluorochemical (PFC) emulsion have been performed in rats. Injection of the emulsion was followed by changes in lymphoid tissue weights, comparable but not identical to those produced by the commercial formulation, Fluosol-DA 20% (F-DA). Peritoneal injection of either the novel emulsion or F-DA enhanced the humoral immune response to intraperitoneally-injected sheep red blood cells (SRBC) suggesting immunopotentiating properties of emulsion components.
已在大鼠身上进行了新型全氟化合物（PFC）乳剂的生物相容性研究。注射该乳剂后，淋巴组织重量发生变化，与市售制剂氟碳乳剂-DA 20%（F-DA）所产生的变化相似但不完全相同。腹腔注射新型乳剂或F-DA均可增强对腹腔注射绵羊红细胞（SRBC）的体液免疫反应，提示乳剂成分具有免疫增强特性。
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