Novacco Marilisa, Hofmann-Lehmann Regina, Grimm Felix, Meli Marina L, Stirn Martina
Clinical Laboratory, Department for Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, Switzerland; Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Switzerland.
Clinical Laboratory, Department for Clinical Diagnostics and Services, Vetsuisse Faculty, University of Zurich, Switzerland; Center for Clinical Studies, Vetsuisse Faculty, University of Zurich, Switzerland.
Vet Parasitol Reg Stud Reports. 2019 Dec;18:100336. doi: 10.1016/j.vprsr.2019.100336. Epub 2019 Sep 10.
Babesia venatorum was isolated from a captive reindeer calf in Switzerland. The clinical signs consistent with acute babesiosis included hemolytic anemia and hemoglobinuria. The diagnosis was made based on visualization of intraerythrocytic parasites in the stained blood smears and confirmed by PCR analysis of the 18S rRNA gene, with subsequent species identification within Babesia confirmed by sequencing. The reindeer calf was initially treated with supportive care and an antiprotozoal drug (imidocarb dipropionate) but died a few days after hospitalization. Babesia venatorum is also known as Babesia sp. EU1 and can infect different mammalian species, including humans. The current case report aims to increase awareness among veterinarians and reindeer owners about the presence and the associated risk of this zoonotic pathogen. Considering the high morbidity and possible mortality associated with acute babesiosis, captive reindeer should receive tick prevention measures and be tested for subclinical infections in endemic area.
瑞士一只圈养的驯鹿幼崽身上分离出了嗜吞噬细胞无形体。与急性巴贝斯虫病相符的临床症状包括溶血性贫血和血红蛋白尿。诊断基于对染色血涂片内红细胞内寄生虫的观察，并通过对18S rRNA基因的PCR分析得到证实，随后通过测序确认巴贝斯虫属内的物种鉴定。这只驯鹿幼崽最初接受了支持性护理和一种抗原生动物药物（双丙酸咪唑苯脲）治疗，但住院几天后死亡。嗜吞噬细胞无形体也被称为巴贝斯虫属EU1，可感染包括人类在内的不同哺乳动物物种。本病例报告旨在提高兽医和驯鹿所有者对这种人畜共患病原体的存在及其相关风险的认识。考虑到急性巴贝斯虫病的高发病率和可能的死亡率，圈养驯鹿应采取蜱预防措施，并在流行地区进行亚临床感染检测。
