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重度肥胖患者单髁膝关节置换术高失败率:一项至少两年的随访研究。

High Failure Rates for Unicompartmental Knee Arthroplasty in Morbidly Obese Patients: A Two-Year Minimum Follow-Up Study.

机构信息

Department of Orthopaedic Surgery, University of Missouri, Columbia, MO.

出版信息

J Arthroplasty. 2020 Apr;35(4):989-996. doi: 10.1016/j.arth.2019.11.003. Epub 2019 Nov 13.

DOI:10.1016/j.arth.2019.11.003
PMID:31796233
Abstract

BACKGROUND

Several recent studies have recommended offering unicompartmental knee arthroplasty (UKA) to all patients regardless of body mass index (BMI). The aim of this investigation was to evaluate the proposition that UKA can indeed be offered to the morbidly-obese and super-obese (morbidly-obese, BMI ≥ 40 kg/m) without compromising results or survivorship.

METHODS

We retrospectively reviewed mobile-bearing medial UKA procedures performed at our facility from January 2012 to May 2015 with a minimum of 2-year follow-up. The study cohort was divided into patients with morbid obesity (BMI ≥ 40 kg/m) and those without morbid obesity (BMI < 40 kg/m). A detailed medical record review was performed. Extracted outcome data included the frequency of (1) major revision procedures (components revised), (2) minor secondary procedures (components not revised), (3) infection procedures, and (4) recommendations for revision.

RESULTS

We found 152 patients (190 knees) who met criteria for inclusion. Mean follow-up duration was 3.4 years (range: 2.0-6.8 years). Major revision surgery occurred more frequently in the morbid-obesity UKA group (15.7% vs 3.0%, P < .01). Rates of minor secondary surgery and infection were comparable for both groups. Most failures in the morbid-obesity UKA group (85.7%) were due to disease progression involving other compartments or mobile-bearing instability.

CONCLUSION

We found the rate of early major revision surgery in morbidly-obese patients undergoing UKA to be over 5-times greater than that of other patients. Failure was predominantly due to disease progression in other compartments or mobile-bearing instability. Further study is warranted and needed before expanding UKA indications to the morbidly-obese population.

摘要

背景

最近有几项研究建议无论体重指数(BMI)如何,都向所有患者提供单髁膝关节置换术(UKA)。本研究旨在评估UKA 确实可以提供给病态肥胖和超级肥胖患者(病态肥胖,BMI≥40kg/m)而不会影响结果或存活率的观点。

方法

我们回顾性地审查了 2012 年 1 月至 2015 年 5 月在我们机构进行的活动衬垫内侧 UKA 手术,随访时间至少为 2 年。研究队列分为病态肥胖患者(BMI≥40kg/m)和非病态肥胖患者(BMI<40kg/m)。对详细的病历进行了审查。提取的结果数据包括(1)主要翻修手术(翻修组件)的频率、(2)次要二次手术(未翻修组件)的频率、(3)感染手术的频率以及(4)翻修建议的频率。

结果

我们发现符合纳入标准的有 152 名患者(190 膝)。平均随访时间为 3.4 年(范围:2.0-6.8 年)。病态肥胖 UKA 组发生主要翻修手术的频率更高(15.7% vs. 3.0%,P<.01)。两组次要二次手术和感染的发生率相似。病态肥胖 UKA 组的大多数失败(85.7%)是由于其他部位的疾病进展或活动衬垫不稳定。

结论

我们发现病态肥胖患者接受 UKA 的早期主要翻修手术的发生率是其他患者的 5 倍以上。失败主要是由于其他部位的疾病进展或活动衬垫不稳定。在将 UKA 适应证扩大到病态肥胖人群之前,还需要进一步研究和验证。

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