Drosos K, Köhler G, Hofmann I, Kälble T
Klinik für Urologie und Kinderurologie, Klinikum Fulda.
Institut für Pathologie, Klinikum Fulda.
Aktuelle Urol. 2022 Aug;53(4):354-357. doi: 10.1055/a-1032-8126. Epub 2019 Dec 3.
Verumontanum mucosal gland hyperplasia (VMGH) is a benign microacinar proliferative lesion, which occurs exclusively in the verumontanum and the posterior urethra and is one of the lesions that may be confused with a low-risk adenocarcinoma of the prostate gland.We present the case of a 72-year-old male patient who underwent radical prostatectomy due to an adenocarcinoma of the prostate gland (pT2c pN0 cM0 R0, Gleason Score: 3 + 3 = 6). Five years after the operation, we sonographically detected a 3x2 cm large tumour in the prostate bed. While our first assumption was a PSA-negative local recurrence following radical prostatectomy, a comprehensive histological examination along with the clinical evaluation led us to the diagnosis of a VMGH. VMGH is a less well-known differential diagnosis of PSA-negative local recurrence following radical prostatectomy, whose clinical manifestation should be presented.
精阜黏膜腺增生(VMGH)是一种良性微腺泡增生性病变,仅发生于精阜和后尿道,是可能与前列腺低风险腺癌相混淆的病变之一。我们报告一例72岁男性患者,因前列腺腺癌(pT2c pN0 cM0 R0, Gleason评分:3+3=6)接受了根治性前列腺切除术。术后五年,我们在前列腺床超声检查发现一个3×2cm大小的肿瘤。虽然我们最初的推测是根治性前列腺切除术后PSA阴性的局部复发,但全面的组织学检查及临床评估使我们诊断为VMGH。VMGH是根治性前列腺切除术后PSA阴性局部复发的一种较不为人知的鉴别诊断,应呈现其临床表现。