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[心肌血运重建术中的变异型心绞痛。71例患者的心血管并发症(作者译)]

[Prinzmetal's angina during myocardial revascularisation. Cardiovascular complications in 71 patients (author's transl)].

作者信息

Fontaine B, Bertrandias E, Chelly J, Kieffer J P, Tournay D, Peyrat D, Passelecq J

出版信息

Anesth Analg (Paris). 1979;36(11-12):545-50.

PMID:317982
Abstract

71 patients undergo myocardial revascularisation for Prinzmetal's angina; among them, 50 p. cent are operated upon in emergency according to three ways of anaesthesia: neuroleptanalgesia, analgesic anaesthesia, combined anaesthesia. The authors lay stress on the importance of per- and post-operative complications: electrocardiographic ischemia in 22 p. cent of the cases, severe ventricular excitability perturbations were observed in 21 p. cent, myocardial necrosis in 14 p. cent, cardiovascular collapse in 21 p. cent and hypertensions in 22 p cent. These complications are often associated. In the discussion, the authors underline anesthetic induction as a cause of Prinzmetal's angina in 50 p. cent of the cases. They put the accent on the severity of peroperative crisis followed in 50 p. cent of the cases by serious ventricular excitability perturbations. In 25 p. cent of the cases myocardial necrosis is a complication of the spasm of a coronary artery. In this field, posterior necrosis are more frequent and correspond to the spasm of the right coronary artery. All the patients of this series, except one, develop necrosis in the spastic area (by-passed or not). Per-operative hypertension has no incidence on the occurrence of post-operative complications. Lastly, continuous per-operative infusions of nitroglycerine has been performed in several patients in order to reduce morbidity of this type of surgery.

摘要

71例患者因变异型心绞痛接受心肌血运重建术;其中,50%的患者根据三种麻醉方式在急诊情况下接受手术:神经安定镇痛、镇痛麻醉、复合麻醉。作者强调了围手术期和术后并发症的重要性:22%的病例出现心电图缺血,21%观察到严重的心室兴奋性紊乱,14%出现心肌坏死,21%发生心血管虚脱,22%出现高血压。这些并发症常相互关联。在讨论中,作者强调在50%的病例中麻醉诱导是变异型心绞痛的一个原因。他们强调手术期危机的严重性,50%的病例随后出现严重的心室兴奋性紊乱。在25%的病例中,心肌坏死是冠状动脉痉挛的并发症。在这方面,后壁坏死更常见,对应于右冠状动脉痉挛。该系列所有患者,除1例之外,均在痉挛区域(无论是否进行搭桥)发生坏死。手术期高血压对术后并发症的发生无影响。最后,为降低此类手术的发病率,对数名患者进行了术中持续输注硝酸甘油。

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