Pennec Y L, Gentric A H, Jouquan J R, Youinou P
Department of Internal Medicine, Medical School Hospital, Brest, France.
Clin Exp Rheumatol. 1988 Jul-Sep;6(3):293-6.
Polymorphonuclear (PMN) cell functions were evaluated in twenty-two patients with primary Sjögren's syndrome (SS) and 45 healthy controls. Adherence, phagocytosis, chemiluminescence and bactericidal ability were not significantly reduced in Sjögren's syndrome patients. Chemotaxis and chemokinesis were markedly reduced in SS patients and the results of the former test correlated well with those of the latter. These observations suggest that the decrease in PMN cell mobility is attributable both to a primary cell abnormality and a serum inhibitory effect.
对22例原发性干燥综合征（SS）患者和45名健康对照者的多形核（PMN）细胞功能进行了评估。干燥综合征患者的黏附、吞噬、化学发光和杀菌能力没有显著降低。干燥综合征患者的趋化性和化学运动性明显降低，且前一项测试结果与后一项测试结果密切相关。这些观察结果表明，PMN细胞迁移能力的下降既归因于原发性细胞异常，也归因于血清抑制作用。
