TRUE检测的欧洲多中心研究。

European multicenter study of the TRUE Test.

作者信息

Lachapelle J M, Bruynzeel D P, Ducombs G, Hannuksela M, Ring J, White I R, Wilkinson J, Fischer T, Billberg K

机构信息

Unit and Laboratory of Occupational and Environmental Dermatology, Louvain University, Brussels, Belgium.

出版信息

Contact Dermatitis. 1988 Aug;19(2):91-7. doi: 10.1111/j.1600-0536.1988.tb05504.x.

DOI:10.1111/j.1600-0536.1988.tb05504.x

PMID:3180789

Abstract

A new, standardized, ready-to-apply patch test, the TRUE Test, has been evaluated on 698 consecutive patients with suspected contact dermatitis. The patients were tested with 12 different allergens. Simultaneously, the same 12 allergens in pet. (Trolab) were applied symmetrically to the opposite side of the upper back using the conventional Finn Chamber technique. There were positive test reactions to all 12 allergens tested in the patient group. The concordance of positive reactions between the TRUE Test and the Finn Chamber test was 67%; 13% of all positive reactions were recorded only for the TRUE Test and 20% only for the Finn Chamber method. The frequency of questionable and irritant reactions was of the same low order of magnitude for both test methods; such reactions were recorded in around 2% of all test patches.

摘要

一种新型的、标准化的、即用型斑贴试验——TRUE试验，已在698例连续的疑似接触性皮炎患者身上进行了评估。用12种不同的变应原对患者进行检测。同时，使用传统的芬兰小室技术，将12种相同变应原的凡士林制剂（Trolab）对称地涂在上背部的另一侧。患者组对所有12种检测变应原均有阳性试验反应。TRUE试验和芬兰小室试验之间阳性反应的一致性为67%；所有阳性反应中，13%仅在TRUE试验中记录到，20%仅在芬兰小室试验中记录到。两种试验方法中可疑和刺激性反应的频率处于相同的低数量级；此类反应在所有试验贴片的约2%中记录到。