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对100例连续患者进行的Epiquick斑贴试验结果的左右侧对比研究。

A left versus right side comparative study of Epiquick patch test results in 100 consecutive patients.

作者信息

Lachapelle J M

机构信息

Unit and Laboratory of Occupational and Environmental Dermatology, Louvain University, Belgium.

出版信息

Contact Dermatitis. 1989 Jan;20(1):51-6. doi: 10.1111/j.1600-0536.1989.tb03095.x.

Abstract

4 strips of 5 Epiquick patch tests (19 allergens plus 1 control) were applied symmetrically in duplicate on the left and right sides of the upper back in 100 consecutive patients. 70 positive allergic patch test reactions were recorded on the left side and 67 on the right side. 67 positive reactions were concordant on both sides (64 with the same score of intensity and 3 with a different score). 3 positive reactions (in 2 patients) on the left side were negative on the right side (1 TMTD, 1 cobalt chloride and 1 wool alcohols). At rechallenge 6 weeks later, they were positive. No explanation could be found for negative results at the first challenge on one side and not on the other. The rate of non-reproducible positive results to the overall number of positive reactions was 4.2%. The good reproducibility rate (95.8%) provides useful information for further comparative studies.

摘要

在100例连续患者的上背部左右两侧对称重复应用4条包含5个Epiquick斑贴试验(19种变应原加1种对照)。左侧记录到70例阳性变应原斑贴试验反应,右侧记录到67例。两侧有67例阳性反应一致(64例强度评分相同,3例评分不同)。左侧3例阳性反应(2例患者)在右侧为阴性(1例福美双、1例氯化钴和1例羊毛醇)。6周后再次激发时,这些反应呈阳性。对于一侧首次激发结果为阴性而另一侧为阳性的情况,未找到原因。不可重复的阳性结果占阳性反应总数的比例为4.2%。良好的可重复性率(95.8%)为进一步的比较研究提供了有用信息。

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