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美国老年人群体中处方阿片类药物滥用的动机。

Prescription Opioid Misuse Motives in US Older Adults.

机构信息

Department of Psychology, Texas State University, San Marcos, Texas.

Peter Lamy Center on Drug Therapy and Aging, and Department of Pharmaceutical Health Services Research, School of Pharmacy, University of Maryland, Baltimore, Maryland.

出版信息

Pain Med. 2020 Oct 1;21(10):2237-2243. doi: 10.1093/pm/pnz304.

Abstract

OBJECTIVES

To evaluate age-based differences in prescription opioid misuse (POM) motives and to evaluate substance use and mental and physical health correlates of POM motive categories in older adults.

DESIGN

Data were from the National Survey on Drug Use and Health (NSDUH), a nationally representative US survey.

SETTING

The NSDUH is a household survey.

SUBJECTS

A total of 5,826 US residents with past-year POM; 415 were 50 years and older (7.1%).

METHODS

Nine POM motives were assessed among those engaged in past-year POM, grouped into three categories: solely physical pain relief, solely non-pain relief, or mixed motives. Prevalence of POM motives were calculated by age group, with logistic models examining age-based differences. Finally, odds of substance use and mental and physical health correlates by motive category were calculated via logistic models in older adults.

RESULTS

POM motivated solely by physical pain relief increased from 35.1% in young adults to 65.4% in older adults; in older adults, 84.7% of POM episodes involved pain relief as a motive. POM for solely non-pain relief or mixed motives was associated with greater odds, vs pain relief only, of past-year benzodiazepine misuse (odds ratio [OR] = 4.43 and 6.15, respectively), any substance use disorder (OR = 5.57 and 5.60, respectively), and suicidal ideation (OR = 4.05 and 3.56, respectively) in older adults.

CONCLUSIONS

. POM motives change over the lifespan, with increasing POM for pain relief with aging. Comprehensive nonopioid pain management is needed for those engaged in POM for pain relief, and substance use and mental health treatment are needed for those with non-pain relief motives.

摘要

目的

评估基于年龄的处方阿片类药物滥用(POM)动机差异,并评估老年人中 POM 动机类别的物质使用和精神及身体健康相关性。

设计

数据来自国家药物使用和健康调查(NSDUH),这是一项具有全国代表性的美国调查。

设置

NSDUH 是一项家庭调查。

受试者

共有 5826 名过去一年有 POM 的美国居民;415 名年龄在 50 岁及以上(7.1%)。

方法

在过去一年中有 POM 的人群中评估了 9 种 POM 动机,分为三类:单纯躯体疼痛缓解、单纯非疼痛缓解或混合动机。按年龄组计算 POM 动机的发生率,并使用逻辑模型检验年龄差异。最后,通过逻辑模型计算老年人群中每种动机类别与物质使用和精神及身体健康相关性的比值比。

结果

单纯因躯体疼痛缓解而使用 POM 的比例从年轻人中的 35.1%增加到老年人中的 65.4%;在老年人中,84.7%的 POM 发作涉及缓解疼痛作为动机。与单纯缓解疼痛相比,单纯为非疼痛缓解或混合动机的 POM 与过去一年苯二氮䓬类药物滥用(比值比[OR]分别为 4.43 和 6.15)、任何物质使用障碍(OR 分别为 5.57 和 5.60)和自杀意念(OR 分别为 4.05 和 3.56)的相关性更高。

结论

POM 动机随年龄增长而变化,随着年龄的增长,为缓解疼痛而使用 POM 的情况增加。对于因缓解疼痛而使用 POM 的人群,需要进行全面的非阿片类疼痛管理,对于非疼痛缓解动机的人群,需要进行物质使用和心理健康治疗。

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