Department of Medicine, Division of Geriatric Medicine and Palliative Care, New York University School of Medicine, 550 First Avenue, BCD 615, New York, NY 10016 USA; Department of Population Health, New York University Langone Medical Center, 550 First Avenue, New York, NY 10016 USA; Center for Drug Use and HIV/HCV Research, New York University Rory Meyers College of Nursing, 433 First Avenue, 7th Floor, New York, NY 10010 USA.
Department of Population Health, New York University Langone Medical Center, 550 First Avenue, New York, NY 10016 USA; Center for Drug Use and HIV/HCV Research, New York University Rory Meyers College of Nursing, 433 First Avenue, 7th Floor, New York, NY 10010 USA.
Drug Alcohol Depend. 2018 Oct 1;191:374-381. doi: 10.1016/j.drugalcdep.2018.07.006. Epub 2018 Sep 6.
Marijuana use is increasing among middle-aged and older adults in the US, but little is understood of its pattern of use by this population.
We performed a cross-sectional analysis of responses from 17,608 adults aged ≥50 years from the 2015 and 2016 administrations of the National Survey on Drug Use and Health. Prevalence of past-year marijuana use was estimated and compared between middle-aged adults (age 50-64) and older adults (≥65). Characteristics of past-year marijuana users including demographics, substance use, chronic disease, and emergency room use, were compared to non-marijuana users and stratified by age group. Marijuana use characteristics were also compared between middle-aged and older adults. We used multivariable logistic regression to determine correlates of past-year marijuana use.
Prevalence of past-year marijuana use was 9.0% among adults aged 50-64 and 2.9% among adults aged ≥65. Prevalence of past-year alcohol use disorder (AUD), nicotine dependence, cocaine use, and misuse of prescription medications (i.e., opioids, sedatives, tranquilizers) were higher among marijuana users compared to non-users. In adjusted models, initiation of marijuana use <19 years of age [adjusted odds ratio (AOR) = 13.43, 95% confidence interval (CI) 9.60, 18.78)], AUD (AOR = 2.11, 95% CI 1.51, 2.94), prescription opioid misuse (AOR 2.49, 95% CI 1.61, 3.85), nicotine dependence (AOR = 1.90, 95% CI 1.59, 2.26), and cocaine use (AOR 7.43, 95% CI 4.23, 13.03), were all associated with increased odds of past-year marijuana use.
Marijuana use is becoming more prevalent in this population and users are also at high risk for other drug use.
在美国,中年和老年人群体中使用大麻的情况正在增加,但人们对这一人群的使用模式知之甚少。
我们对 2015 年和 2016 年全国药物使用与健康调查中 17608 名年龄在 50 岁及以上的成年人的回答进行了横断面分析。估计了过去一年大麻使用的流行率,并在中年成年人(50-64 岁)和老年人(≥65 岁)之间进行了比较。过去一年大麻使用者的特征,包括人口统计学、物质使用、慢性疾病和急诊室使用情况,与非大麻使用者进行了比较,并按年龄组进行了分层。还比较了中年和老年成年人之间的大麻使用特征。我们使用多变量逻辑回归来确定过去一年大麻使用的相关因素。
50-64 岁成年人过去一年大麻使用的流行率为 9.0%,≥65 岁成年人的流行率为 2.9%。与非使用者相比,过去一年酒精使用障碍(AUD)、尼古丁依赖、可卡因使用和处方药物(即阿片类药物、镇静剂、安定剂)滥用的发生率更高。在调整后的模型中,19 岁以下开始使用大麻[调整后的优势比(AOR)=13.43,95%置信区间(CI)9.60,18.78]、AUD(AOR=2.11,95%CI 1.51,2.94)、处方类阿片药物滥用(AOR 2.49,95%CI 1.61,3.85)、尼古丁依赖(AOR=1.90,95%CI 1.59,2.26)和可卡因使用(AOR 7.43,95%CI 4.23,13.03)均与过去一年大麻使用的几率增加相关。
大麻在这一人群中的使用越来越普遍,使用者也有很高的其他药物使用风险。