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联苯苄唑洗剂或芬替康唑洗剂治疗花斑癣的双盲研究。

Double-blind study with fenticonazole or bifonazole lotions in pityriasis versicolor.

作者信息

Aste N, Pau M, Cordaro C I, Biggio P

机构信息

University Dermatological Clinic, University of Cagliari, Italy.

出版信息

Int J Clin Pharmacol Res. 1988;8(4):271-3.

PMID:3182117
Abstract

The efficacy of fenticonazole 2% lotion was studied in patients suffering from pityriasis versicolor in a double-blind comparison with bifonazole 1% lotion, both applied once daily for three weeks. Forty-six patients were recruited and randomly allocated to one or other treatment group. Clinical and mycological examinations, performed at baseline and at weekly intervals, have shown an excellent response to both treatments. Two cases of mild transient desquamation were reported in the fenticonazole group. Fenticonazole 2% lotion appears active in the treatment of pityriasis versicolor and its efficacy is comparable to that of bifonazole.

摘要

在一项双盲研究中,对46例花斑癣患者比较了2%联苯苄唑洗剂和1%联苯苄唑洗剂的疗效,两种洗剂均每日使用一次,持续三周。招募了46例患者并随机分配到两个治疗组中的一组。在基线和每周进行的临床和真菌学检查表明,两种治疗均有良好疗效。联苯苄唑组报告了2例轻度短暂脱屑病例。2%联苯苄唑洗剂在治疗花斑癣方面似乎有效,其疗效与联苯苄唑相当。

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