辅酶Q10在大鼠体内的皮肤渗透情况。
Skin penetration of CoQ10 in the rat.
作者信息
Giovannini L, Bertelli A A, Scalori V, Dell'Osso L, Alessandrì M G, Mian M
机构信息
Institute of Pharmacology, School of Medicine, University of Pisa, Italy.
出版信息
Int J Tissue React. 1988;10(2):103-5.
PMID:3182185
Abstract
Skin penetration of coenzyme Q10 (CoQ10) was investigated after topical treatment in the rat. The drug was suspended in olive oil and administered at two different concentrations. Coenzyme levels were found to be directly related to the concentrations employed and the contact time. CoQ10 topical treatment might therefore be proposed as a good pharmacological tool in dermatology and cosmetology.
摘要
在大鼠局部给药后，对辅酶Q10（CoQ10）的皮肤渗透情况进行了研究。该药物悬浮于橄榄油中，并以两种不同浓度给药。发现辅酶水平与所用浓度及接触时间直接相关。因此，CoQ10局部治疗可能被推荐为皮肤科和美容领域一种良好的药理学手段。
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