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一名年轻女性的乳糜泻危象:提高对一种危及生命病症的认识

Celiac Crisis in a Young Woman: Raising Awareness of a Life-Threatening Condition.

作者信息

Jameshorani Maryam, Pourshams Akram, Sadeghi Anahita, Saffar Hiva, Malekzadeh Reza

机构信息

Zanjan University of Medical Sciences. Tehran, Iran.

Disease Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran.

出版信息

Middle East J Dig Dis. 2019 Oct;11(4):230-233. doi: 10.15171/mejdd.2019.154. Epub 2019 Nov 5.

Abstract

Celiac crisis is a rare, acute, and life-threatening presentation of celiac disease. Its clinical presentations consist of severe watery non-bloody diarrhea, electrolyte disturbances (i.e. hypokalemia, hyponatremia, hypomagnesemia, hypocalcemia, and metabolic acidosis), hypoproteinemia, and dehydration. Here we present a 33-year-old woman who referred with profuse diarrhea, weight loss, hemodynamic instability, hypokalemia, hypoproteinemia, ascites, pancytopenia, and iron deficiency anemia. She used herbal medicines for constipation and had severe weakness after her childbirth. The patient was diagnosed as having celiac disease through pathological and serological evaluations 10 months earlier. Diagnosis of celiac crisis after ruling out the other causes of resistant celiac was made and she was treated with steroids.

摘要

乳糜泻危象是乳糜泻一种罕见、急性且危及生命的表现形式。其临床表现包括严重的水样非血性腹泻、电解质紊乱(即低钾血症、低钠血症、低镁血症、低钙血症和代谢性酸中毒)、低蛋白血症和脱水。在此,我们报告一名33岁女性,她因大量腹泻、体重减轻、血流动力学不稳定、低钾血症、低蛋白血症、腹水、全血细胞减少和缺铁性贫血前来就诊。她曾使用草药治疗便秘,产后极度虚弱。该患者10个月前通过病理和血清学评估被诊断为乳糜泻。在排除其他难治性乳糜泻病因后诊断为乳糜泻危象,并对她进行了类固醇治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/963c/6895852/08de7dac0b3e/mejdd-11-230-g001.jpg

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