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[小儿乳糜泻危象与急性手足搐搦。病例报告]

[Celiac crisis and acute tetany in pediatrics. Case report].

作者信息

Sbruzzi Agustina Del Rosario, Torres Federico, Sommaruga Horacio, Ameri Camila, Yarcho Maria, Gonzalez Maria Fernanda

机构信息

Hospital General de Niños Pedro de Elizalde. Buenos Aires, Argentina.

Jefe del Servicio de Gastroenterología, Hospital General de Niños Pedro de Elizalde. Buenos Aires, Argentina.

出版信息

Rev Gastroenterol Peru. 2022 Jan-Mar;42(1):45-47.

Abstract

Celiac disease is an immune-mediated systemic disease with a wide spectrum of clinical presentations. The term celiac crisis describes the acute and potentially fatal form. Clinically it is characterized by severe diarrhea, dehydration, and metabolic disturbances. The case of a 7-year-old male patient attending the ward with tetany, lower limb edema, steatorrhea and weight loss of 8 months of evolution is reported, with analytical findings of hypocalcemia, hypomagnesemia, hypokalemia and coagulopathy. The diagnosis of celiac crisis was made on the basis of serological and clinical findings compatible with celiac disease in the context of severe metabolic abnormalities and acute malnutrition, later confirmed by pathological anatomy. The importance of this report lies in reviewing the characteristics of this serious entity, which requires a high index of suspicion for its diagnosis.

摘要

乳糜泻是一种免疫介导的全身性疾病,临床表现多样。乳糜泻危象这一术语描述的是急性且可能致命的形式。临床上其特征为严重腹泻、脱水和代谢紊乱。本文报告了一名7岁男性患者,因手足搐搦、下肢水肿、脂肪泻及8个月来体重减轻而入住病房,分析检查发现有低钙血症、低镁血症、低钾血症及凝血障碍。乳糜泻危象的诊断基于在严重代谢异常和急性营养不良背景下与乳糜泻相符的血清学及临床检查结果,后经病理解剖得以证实。本报告的重要性在于回顾这一严重疾病的特征,其诊断需要高度的怀疑指数。

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