Feng J, Liu Z W, Cai S W, Xin X L, Chen J Y, Wang P F, He L, Ma H X
Department of Hepatobiliary Surgery, Chinese People's Liberation Army General Hospital First Medical Center, Beijing 100853, China.
Zhonghua Wai Ke Za Zhi. 2019 Dec 1;57(12):917-920. doi: 10.3760/cma.j.issn.0529-5815.2019.12.009.
To examine the effectiveness of non-operative of colonic fistula following acute pancreatitis. Retrospective analysis of 354 patients with acute pancreatitis who were admitted to Department of Hepatobiliary Surgery of Chinese People's Liberation Army General Hospital from January 2013 to December 2018. Age of the patients was (46±14) years (range: 14-85 years); 249 cases (70.3%) were males. There were 41 cases of acute edematous pancreatitis and 313 cases of acute necrotising pancreatitis. Two hundred and fifteen cases were diagnosed as moderate severe acute pancreatitis and 139 were diagnosed as severe acute pancreatitis. Among 313 cases of acute necrotising pancreatitis, 62 cases underwent non-surgical treatment, 251 cases underwent surgical treatment in which 218 of minimal access retroperitoneal pancreatic necrosectomy underwent percutaneous nephroliguectomy with peripancreatic necrotic tissue removal technique. There were 15 cases of colon fistula following acute necrotising pancreatitis, and the incidence rate was 4.2%(15/354). There were 7 males and 8 females, with age of (39±8) years (range: 27 to 50 years). The median interval between acute pancreatitis onset and diagnosis of colonic fistula was 71 days(27-134) days. Two cases occurred at the hepatic flexure of the colon, 4 cases at transverse colon, and 9 cases at splenic flexure of colon. Of the 354 patients, 39 cases died and the mortality was 11.0%. Two patients underwent laparotomy, and one of them died. The remaining 13 patients underwent non-surgical treatment and were discharged. Acute pancreatitis with colonic fistula can be treated with non-surgical treatment and can achieve good prognosis.
探讨急性胰腺炎后结肠瘘非手术治疗的有效性。回顾性分析2013年1月至2018年12月在中国人民解放军总医院肝胆外科住院的354例急性胰腺炎患者。患者年龄为(46±14)岁(范围:14 - 85岁);男性249例(70.3%)。急性水肿性胰腺炎41例,急性坏死性胰腺炎313例。215例诊断为中度重症急性胰腺炎,139例诊断为重症急性胰腺炎。在313例急性坏死性胰腺炎中,62例接受非手术治疗,251例接受手术治疗,其中218例行微创腹膜后胰腺坏死组织清除术并经皮肾镜取石术清除胰周坏死组织。急性坏死性胰腺炎后发生结肠瘘15例,发生率为4.2%(15/354)。男性7例,女性8例,年龄为(39±8)岁(范围:27至50岁)。急性胰腺炎发病至结肠瘘诊断的中位间隔时间为71天(27 - 134天)。2例发生于结肠肝曲,4例发生于横结肠,9例发生于结肠脾曲。354例患者中,39例死亡(死亡率11.0%)。2例患者接受剖腹手术,其中1例死亡。其余13例患者接受非手术治疗后出院。急性胰腺炎合并结肠瘘可采用非手术治疗并可取得良好预后。