Ishimaru Hideki, Yoshimi Satomi, Akita Sadanori
Department of Radiology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan.
Department of Radiology, National Nagasaki Medical Center, Nagasaki, Japan.
Adv Wound Care (New Rochelle). 2019 Jun 1;8(6):256-262. doi: 10.1089/wound.2018.0846. Epub 2019 Jun 6.
To clarify clinically challenging palpebral arteriovenous malformations (AVMs) and to propose a novel therapeutic modality, we developed a multi-disciplinary approach for the management of AVMs with ulcer. First, the central retinal artery was secured with embolization by the transophthalmic arterial, a terminal branch of the internal carotid artery (ICA), and then, the branches of the external carotid artery (ECA) were embolized to cause a response in the AVM vasculature followed by sclerotherapy and surgery. Over a 3-year follow-up of palpebral and periorbital AVMs in four females and one male 20 to 50 years of age with a mean age of 38 years, complete remission of the lesions were seen with no major complication, such as blindness, ptosis, or cerebral infarction, with functionally sound and esthetically acceptable results, with no recurrence or worsening even with one case of ulceration postembolization. Planned treatment of palpebral and periorbital AVMs, which have been often left untreated because of their complex vasculature and a risk of total blindness due to occlusion of the central retinal artery. A "wait-and-watch" approach is frequently taken. It is important to secure the periphery to the bifurcation of the central retinal artery of the ICA, and then, embolization through the ECA results in complete remission of the lesion, followed by sclerotherapy and surgery, which are successful both in terms of function and esthetics. First, securing the central retinal artery leads to safer and complete resolution of palpebral and periorbital AVMs; wounding or therapeutic complications such as skin necrosis may be seen, but this approach results in complete remission in 3 years with no major complications.
为了明确临床上具有挑战性的眼睑动静脉畸形(AVM)并提出一种新的治疗方式,我们开发了一种多学科方法来治疗伴有溃疡的AVM。首先,通过经眼动脉(颈内动脉(ICA)的终末分支)栓塞来确保视网膜中央动脉的安全,然后栓塞颈外动脉(ECA)的分支,以引起AVM脉管系统的反应,随后进行硬化疗法和手术。对4名女性和1名男性(年龄在20至50岁之间,平均年龄38岁)的眼睑和眶周AVM进行了为期3年的随访,病变完全缓解,无失明、上睑下垂或脑梗死等重大并发症,功能良好且美观效果可接受,即使有1例栓塞后溃疡病例,也无复发或病情恶化。眼睑和眶周AVM由于其复杂的脉管系统以及视网膜中央动脉闭塞导致完全失明的风险,常常未得到治疗。通常采取“观察等待”的方法。确保ICA视网膜中央动脉分叉处的周边安全很重要,然后通过ECA进行栓塞可使病变完全缓解,随后进行硬化疗法和手术,在功能和美学方面均取得成功。首先,确保视网膜中央动脉的安全可实现眼睑和眶周AVM更安全、更完全的消退;可能会出现伤口或治疗并发症,如皮肤坏死,但这种方法在3年内可实现完全缓解,且无重大并发症。