Park So Young, Ahn Seong Hee, Yoo Jun-Il, Chung Youn-Jee, Jeon Yun Kyung, Yoon Byung-Ho, Kim Ha Young, Lee Seung Hun, Lee Jehoon, Hong Seongbin
Division of Endocrinology and Metabolism, Department of Internal Medicine, Kyung Hee University Hospital, Seoul, Korea.
Division of Endocrinology and Metabolism, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
J Bone Metab. 2019 Nov;26(4):213-224. doi: 10.11005/jbm.2019.26.4.213. Epub 2019 Nov 30.
Current evidences continue to support the clinical application of bone turnover markers (BTMs) in the management of postmenopausal osteoporosis. The limitations of bone mineral density measured by dual energy X-ray absorptiomet especially emphasize the beneficial roles of BTMs, such as serum C-terminal telopeptide of type I collagen and serum procollagen type I N-propeptide, as monitoring tools to assess the responses to treatment. Therefore, the proper application and assessment of BTM in clinical practice is very important. However, their use in Korea is still insufficient. Therefore, the BTM committee has set up by the Korean Society for Bone and Mineral Research have been constituted and provided a position statement which will suggest on the clinical application of BTM for the management of postmenopausal osteoporosis in Korea.
目前的证据继续支持骨转换标志物（BTMs）在绝经后骨质疏松症管理中的临床应用。双能X线吸收法测量骨密度的局限性尤其凸显了BTMs的有益作用，如血清I型胶原C端肽和血清I型前胶原N端前肽，作为评估治疗反应的监测工具。因此，在临床实践中正确应用和评估BTM非常重要。然而，它们在韩国的使用仍然不足。因此，韩国骨与矿物质研究学会成立了BTM委员会，并发布了一份立场声明，就BTM在韩国绝经后骨质疏松症管理中的临床应用提出建议。
