Molecular Enzymology group, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Appl Microbiol Biotechnol. 2020 Feb;104(3):925-933. doi: 10.1007/s00253-019-10292-5. Epub 2019 Dec 13.
Indigo is one of the oldest textile dyes and was originally prepared from plant material. Nowadays, indigo is chemically synthesized at a large scale to satisfy the demand for dyeing jeans. The current indigo production processes are based on fossil feedstocks; therefore, it is highly attractive to develop a more sustainable and environmentally friendly biotechnological process for the production of this popular dye. In the past decades, a number of natural and engineered enzymes have been identified that can be used for the synthesis of indigo. This mini-review provides an overview of the various microbial enzymes which are able to produce indigo and discusses the advantages and disadvantages of each biocatalytic system.
靛蓝是最古老的纺织染料之一，最初是由植物材料制成的。如今，靛蓝已被大规模化学合成，以满足牛仔裤染色的需求。目前的靛蓝生产工艺基于化石原料；因此，开发一种更可持续和环保的生物技术工艺来生产这种流行的染料是非常有吸引力的。在过去的几十年中，已经鉴定出许多天然和工程酶可用于靛蓝的合成。本综述概述了能够产生靛蓝的各种微生物酶，并讨论了每个生物催化系统的优缺点。
