Launey Y, Le Gac G, Le Reste P-J, Gauvrit J-Y, Morandi X, Seguin P
Critical care unit, department of anesthesiology and critical care medicine, Rennes university hospital, 2, rue Henri Le Guilloux, 35033 Rennes, France.
Critical care unit, department of anesthesiology and critical care medicine, Rennes university hospital, 2, rue Henri Le Guilloux, 35033 Rennes, France.
Neurochirurgie. 2020 Feb;66(1):9-15. doi: 10.1016/j.neuchi.2019.11.001. Epub 2019 Dec 10.
Subarachnoid hemorrhage (SAH) from intracranial aneurysm rupture is an unpredictable event responsible for significant morbidity and mortality. Despite inconsistencies, some studies suggest a potential role of climate conditions in SAH onset. The purpose of this study was to determine the impact of climatic and lunar factors on onset of SAH in an oceanic climate such as that of Brittany, France.
All adults with SAH admitted to the neurosurgery department and intensive care unit of the University Hospital of Rennes (France) between January 1st, 2011 and December 31st, 2012 were included. Meteorological variables, their variations, lunar phases and tidal coefficients were compared between days with and without SAH.
We retrospectively included 295 patients with SAH. Mean minimum temperature was significantly lower during days with SAH (7.7±4.7°C versus 8.3±4.6°C; P=0.039); temperature variation between 2 successive days was significantly greater for days with SAH (8.6±4.1°C versus 7.9±3.8°C; P<0.01). Multivariate analysis showed that a 2-day temperature drop greater than or equal to 8°C was associated with 35% increased risk of SAH (odds ratio 1.35 [1.03-1.77]). There were no significant effects of other meteorological variables, lunar phase or tidal coefficient on SAH occurrence.
Low temperature and sudden temperature drop were associated with increased occurrence of SAH in Brittany, France.
颅内动脉瘤破裂引起的蛛网膜下腔出血（SAH）是一种不可预测的事件，会导致严重的发病率和死亡率。尽管存在不一致性，但一些研究表明气候条件在SAH发病中可能起作用。本研究的目的是确定气候和月球因素对法国布列塔尼等海洋性气候地区SAH发病的影响。
纳入2011年1月1日至2012年12月31日期间在法国雷恩大学医院神经外科和重症监护病房收治的所有成年SAH患者。比较有SAH和无SAH的日子之间的气象变量、其变化、月相和潮汐系数。
我们回顾性纳入了295例SAH患者。SAH发生当天的平均最低温度显著更低（7.7±4.7°C对8.3±4.6°C；P=0.039）；SAH发生当天连续两天之间的温度变化显著更大（8.6±4.1°C对7.9±3.8°C；P<0.01）。多变量分析显示，连续两天温度下降大于或等于8°C与SAH风险增加35%相关（比值比为1.35[1.03-1.77]）。其他气象变量、月相或潮汐系数对SAH发生没有显著影响。
在法国布列塔尼，低温和温度骤降与SAH发生率增加有关。
