Kellogg Marissa, Petrov Dimitriy, Agarwal Nitin, Patel Nitesh V, Hansberry David Richard, Agarwal Prateek, Brimacombe Michael, Gandhi Chirag D, Prestigiacomo Charles
Department of Neurology, Oregon Health and Science University, Portland, Oregon, United States.
Department of Neurological Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, United States.
J Neurol Surg A Cent Eur Neurosurg. 2017 May;78(3):238-244. doi: 10.1055/s-0036-1594308. Epub 2016 Nov 30.
Previous studies have suggested relationships between the rupture of intracranial aneurysms and meteorological variables such as season, barometric pressure, and temperature. Our objective was to examine the relationship between the incidence of hospital admissions secondary to aneurysmal subarachnoid hemorrhage (aSAH) and meteorological variables in central New Jersey. The study population consisted of 312 patients who presented to University Hospital in Newark, New Jersey, between January 1, 2003, and December 31, 2008, with aSAH. Days in the 6-year period were classified as nonbleed days (no aSAH), bleed days (one or more aSAHs within 1 calendar day), cluster days (two or more aSAHs within 2 calendar days), and multiple-bleed days (two or more aSAHs within 1 calendar day). The only significant meteorological risk factor for the occurrence of multiple-bleed days was high barometric pressure (1018.5 versus 1016.5 millibars [mbars]; 0.04), but an increase in barometric pressure (+ 2.8 mbars) over the 2 days prior to the multiple-bleed day, although not statistically significant, may be a risk factor ( 0.09). Barometric pressure was also noted to be increased on bleed days (1017.2 versus 1016.5 mbars) and cluster days (1017.7 versus 1016.5 mbars), but this relationship was not significant ( 0.1 and 0.1, respectively). Although aSAH days demonstrated consistently lower temperatures than non-aSAH days and dropping temperatures were consistently found in the days preceding the aSAH, these relationships were not significant. Among meteorological factors, high barometric pressure and low temperature may be risk factors for the onset of aSAH.
以往研究表明，颅内动脉瘤破裂与季节、气压和温度等气象变量之间存在关联。我们的目的是研究新泽西州中部因动脉瘤性蛛网膜下腔出血（aSAH）导致的住院发病率与气象变量之间的关系。研究人群包括2003年1月1日至2008年12月31日期间在新泽西州纽瓦克市大学医院就诊的312例aSAH患者。将这6年中的日子分为非出血日（无aSAH）、出血日（1个日历日内发生1次或多次aSAH）、聚集日（2个日历日内发生2次或更多次aSAH）和多次出血日（1个日历日内发生2次或更多次aSAH）。多次出血日发生的唯一显著气象危险因素是高气压（1018.5对1016.5毫巴[mbars]；P = 0.04），但在多次出血日前2天气压升高（+2.8 mbars），尽管无统计学意义，可能也是一个危险因素（P = 0.09）。出血日（1017.2对1016.5 mbars）和聚集日（1017.7对1016.5 mbars）的气压也有所升高，但这种关系不显著（分别为P = 0.1和P = 0.1）。尽管aSAH日的温度始终低于非aSAH日，且在aSAH前的日子里温度持续下降，但这些关系不显著。在气象因素中，高气压和低温可能是aSAH发病的危险因素。
