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髋关节和膝关节置换术后强化康复中的血液管理

Blood management in enhanced recovery after hip and knee replacement.

作者信息

Dao Pierre, Massin Philippe

机构信息

CMC Ambroise-Paré, 25-27, boulevard Victor-Hugo, 92200 Neuilly-sur-Seine, France.

3, rue de l'Hôtel de Ville, 92200 Neuilly-sur-Seine, France.

出版信息

Orthop Traumatol Surg Res. 2020 Feb;106(1S):S1-S5. doi: 10.1016/j.otsr.2019.05.022. Epub 2019 Dec 10.

Abstract

Enhanced recovery in orthopedic surgery is a global patient management strategy to achieve early functional recovery. Blood management is central to rehabilitation protocols after hip or knee replacement. Coagulation physiology in hip and knee replacement is now well described, showing aggravation of bleeding by hyperfibrinolysis. The present study approaches blood management via 3 questions. 1/How to anticipate and prevent transfusion risk preoperatively? Screening for predictive factors can target the at-risk population, enabling a strategy of preoperative hemoglobin level optimization. 2/How to improve intraoperative hemostasis so as to minimize blood loss? Anti-fibrinolytic and topical hemostatic agents have proven efficacy. Tranexamic acid plays a central role. The impact of the usual surgical techniques, such as pneumatic tourniquet and postoperative drainage, on bleeding needs assessment. 3/How to manage postoperative anemia? Anemia without signs of general intolerance is frequent at discharge, but has been little studied. This raises the question of the medical interest of correcting postoperative anemia. LEVEL OF EVIDENCE: Expert opinion, V.

摘要

骨科手术中的加速康复是一种旨在实现早期功能恢复的全球患者管理策略。血液管理是髋关节或膝关节置换术后康复方案的核心。目前对髋关节和膝关节置换术中的凝血生理已有充分描述,显示出高纤维蛋白溶解会加重出血。本研究通过三个问题探讨血液管理。1/如何在术前预测和预防输血风险?筛查预测因素可针对高危人群,从而制定优化术前血红蛋白水平的策略。2/如何改善术中止血以尽量减少失血?抗纤维蛋白溶解剂和局部止血剂已被证明有效。氨甲环酸起着核心作用。常规手术技术,如充气止血带和术后引流,对出血的影响需要评估。3/如何处理术后贫血?出院时无全身不耐受迹象的贫血很常见,但对此研究较少。这就引发了纠正术后贫血的医学意义问题。证据水平:专家意见,V级

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