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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Agius L, Jaccarini V, Ballantine J A, Ferrito V, Pelter A, Psaila A F, Zammit V A

Fort St. Lucian Marine Station, Old University of Malta.

Comp Biochem Physiol B. 1979;63(1):109-17. doi: 10.1016/0305-0491(79)90242-6.

The photodynamic activity of bonellin, an integumentary chlorin of Bonellia viridis, is investigated. 2. 10(-6) M bonellin solutions haemolyze erythrocytes only in the presence of light. Previous illumination (tungsten lamp 2000-4000 lux for 1 hr) of the bonellin solutions does not affect the results. Under lowered oxygen tensions the bioactivity is depressed. Benzoquinone and singlet oxygen quenchers delay the photodynamic effect. 3. Bonellin (2 x 10(-6) M) destroys echinoid gamete function, depresses oxygen uptake of spermatozoa, and arrests development of echinoid and Bonellia eggs. These effects are produced only in the presence of light. 4. Copper bonellin is not photodynamically active. The role of copper may be to protect against photosensitization.

对博内利绿海蛞蝓的一种体被二氢卟吩——博内林的光动力活性进行了研究。2. 10⁻⁶M的博内林溶液仅在光照条件下才会使红细胞溶血。预先对博内林溶液进行光照（用2000 - 4000勒克斯的钨灯照射1小时）不影响实验结果。在较低的氧张力下，生物活性会降低。苯醌和单线态氧猝灭剂会延迟光动力效应。3. 博内林（2×10⁻⁶M）会破坏海胆配子功能，降低精子的氧气摄取，并阻止海胆和博内利绿海蛞蝓卵子的发育。这些效应仅在光照条件下产生。4. 铜博内林没有光动力活性。铜的作用可能是防止光致敏。

Agius L, Jaccarini V, Ballantine J A, Ferrito V, Pelter A, Psaila A F, Zammit V A

Fort St. Lucian Marine Station, Old University of Malta.

Comp Biochem Physiol B. 1979;63(1):109-17. doi: 10.1016/0305-0491(79)90242-6.

The photodynamic activity of bonellin, an integumentary chlorin of Bonellia viridis, is investigated. 2. 10(-6) M bonellin solutions haemolyze erythrocytes only in the presence of light. Previous illumination (tungsten lamp 2000-4000 lux for 1 hr) of the bonellin solutions does not affect the results. Under lowered oxygen tensions the bioactivity is depressed. Benzoquinone and singlet oxygen quenchers delay the photodynamic effect. 3. Bonellin (2 x 10(-6) M) destroys echinoid gamete function, depresses oxygen uptake of spermatozoa, and arrests development of echinoid and Bonellia eggs. These effects are produced only in the presence of light. 4. Copper bonellin is not photodynamically active. The role of copper may be to protect against photosensitization.

对博内利绿海蛞蝓的一种体被二氢卟吩——博内林的光动力活性进行了研究。2. 10⁻⁶M的博内林溶液仅在光照条件下才会使红细胞溶血。预先对博内林溶液进行光照（用2000 - 4000勒克斯的钨灯照射1小时）不影响实验结果。在较低的氧张力下，生物活性会降低。苯醌和单线态氧猝灭剂会延迟光动力效应。3. 博内林（2×10⁻⁶M）会破坏海胆配子功能，降低精子的氧气摄取，并阻止海胆和博内利绿海蛞蝓卵子的发育。这些效应仅在光照条件下产生。4. 铜博内林没有光动力活性。铜的作用可能是防止光致敏。