School of Environment, Tsinghua University, Beijing 100084, China.
School of Environment, Tsinghua University, Beijing 100084, China.
Environ Int. 2020 Feb;135:105379. doi: 10.1016/j.envint.2019.105379. Epub 2019 Dec 13.
In China, data relating to the historic prevalence of childhood lead poisoning suggest its pervasiveness. This review analysed published epidemiological data on blood lead levels (BLLs) of 735,271 Chinese children aged 0-6 between 1987 and 2017. Among these children, the geometric mean (GM) BLL was 95.1 μg/L (geometric SD = 1.62), and 24.1% suffered lead poisoning (BLL ≥ 100 μg/L). Importantly, there was a temporal decrease in the GM BLL value, from 182.9 μg/L in 1987-1991 to 42.4 μg/L in 2012-2017. However, a rebound was seen in the most recent two years (2016 and 2017). Moreover, the GM BLL among Chinese children has not fallen as low as U.S. children. This indicates that either (1) leaded petrol or lead based-paint exposure sources have not been adequately controlled in China, or (2) other pollution sources, such as industry, traffic, and e-waste, are impacting Chinese children. Drivers behind spatio-temporal variations were explored to provide scientific evidence regarding the prevention of childhood lead poisoning. We found that BLLs among children in the central and eastern areas of China have dropped lower than those in the western area, and that the GM BLL of children living in rural areas now exceeds children in urban areas. These reversals may be associated with the industrial decentralization policy of the late 1980s, when many heavily polluting industries and manufacturers moved away from cities on the east coast. It was discovered that the BLLs of children living in areas associated with mining have remained high (GM BLL = 155.0 μg/L for 2007-2017), and that the lead poisoning rate (LPR) has become exceptionally high in areas associated with e-waste. Finally, the review offers a data comparison with other countries, an overview of potentially influencing factors and sources, as well as some suggested prevention strategies to reduce childhood lead exposure.
在中国,有关儿童铅中毒历史流行率的数据表明其普遍性。本综述分析了 1987 年至 2017 年间 735271 名 0-6 岁中国儿童的血液铅水平(BLL)的已发表的流行病学数据。在这些儿童中,几何均数(GM)BLL 为 95.1μg/L(几何标准差=1.62),24.1%患有铅中毒(BLL≥100μg/L)。重要的是,GM BLL 值呈时间下降趋势,从 1987-1991 年的 182.9μg/L 下降到 2012-2017 年的 42.4μg/L。然而,最近两年(2016 年和 2017 年)出现了反弹。此外,中国儿童的 GM BLL 并未降至美国儿童的水平。这表明(1)在中国,含铅汽油或含铅涂料的暴露源并未得到充分控制,或者(2)工业、交通和电子废物等其他污染源正在影响中国儿童。探索时空变化的驱动因素,为预防儿童铅中毒提供科学依据。我们发现,中国中部和东部地区儿童的 BLL 下降幅度低于西部地区,农村地区儿童的 GM BLL 现在超过了城市地区的儿童。这些逆转可能与 20 世纪 80 年代末的产业分散化政策有关,当时许多重污染的工业和制造商从东部沿海城市迁往内地。研究发现,生活在矿区的儿童的 BLL 一直很高(2007-2017 年 GM BLL 为 155.0μg/L),而生活在电子废物区的儿童的铅中毒率(LPR)异常高。最后,本综述还与其他国家进行了数据比较,概述了可能影响儿童铅暴露的因素和来源,并提出了一些减少儿童铅暴露的预防策略。