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前路颈椎间盘切除并椎间融合器融合技术的长期疗效:多中心研究结果

Long-Term Results of Multiple Anterior Cervical Discectomy with Cage Fusion Technique: Results of Multiple Centre Study.

作者信息

Mostafa Hamdy, Lotfy Mohsen, Wahid M

机构信息

Department of Neurosurgery, Faculty of Medicine, Misr University for Science and Technology, Giza, Egypt.

Department of Neurosurgery, Faculty of Medicine, Cairo University, Cairo, Egypt.

出版信息

Open Access Maced J Med Sci. 2019 Aug 20;7(17):2824-2828. doi: 10.3889/oamjms.2019.631. eCollection 2019 Sep 15.

Abstract

BACKGROUND

Cervical herniation is commonly treated by anterior cervical discectomy and fusion (ACDF) if conservative management has failed in relief of the patient's symptoms. Disc fusion is needed after ACDF as anterior longitudinal ligament will be absent after doing the operation, especially if multiple levels are needed. The occurrence of complications as cage subsidence and adjacent segment failure related to the length of follow up as they are increasing in percentage is directly proportional to the length of follow up.

AIM

Analysis of the results for patients who underwent 3 levels of ACDF with cage fusion for short term and long term follow up in multiple centres as the visual analogue score for neck pain & brachialgia.

METHODS

This retrospective cohort series of 68 patients selected out of 136 patients suffering from 3 levels of degenerative cervical disc disease who were unresponsive to adequate conservative therapy. All cases were treated at one of the neurosurgery departments of 3 different hospitals (Naser institute for research and treatment hospital, Haram hospital for research and treatment and Misr university for science and technology) by the same surgical team in the period from February 2012 to February 2017.

RESULTS

We found in this study;68 patients fulfilling the inclusion criteria, of the 29 patients underwent 3 levels of ACDF starting from C3-4 (42.65%) and 39 patients who underwent 3 levels of ACDF starting from C4-5 (57.35%). Clinical assessment for VAS pain score for both neck pain and radiculopathy were done before the surgery and immediately post-operative and during each time follow up visit and we found statistically significant immediate postoperative improvement. (P < 0.05).

CONCLUSION

Stand-alone three levels of an anterior cervical discectomy with cage fusion technique improved the clinical outcomes on long term follow up.

摘要

背景

如果保守治疗未能缓解患者症状,颈椎间盘突出症通常采用颈椎前路椎间盘切除融合术(ACDF)进行治疗。ACDF术后需要进行椎间盘融合,因为手术后前纵韧带将缺失,尤其是在需要多个节段手术时。与随访时间相关的并发症,如椎间融合器下沉和相邻节段退变,其发生率随着随访时间的延长而增加,二者成正比。

目的

分析多中心短期和长期随访的接受三节段ACDF椎间融合术患者的结果,以评估颈部疼痛和臂痛的视觉模拟评分。

方法

本回顾性队列研究系列共纳入68例患者,这些患者选自136例患有三节段退变性颈椎间盘疾病且对充分保守治疗无反应的患者。所有病例均在2012年2月至2017年期间由同一手术团队在3家不同医院(纳赛尔研究与治疗医院、哈拉姆研究与治疗医院和米斯尔科技大学)的神经外科之一进行治疗。

结果

我们在本研究中发现;68例患者符合纳入标准,其中29例患者从C3-4开始接受三节段ACDF(42.65%),39例患者从C4-5开始接受三节段ACDF(57.35%)。在手术前、术后即刻以及每次随访时对颈部疼痛和神经根病的VAS疼痛评分进行了临床评估,我们发现术后即刻有统计学意义的改善。(P<0.05)。

结论

单纯三节段颈椎前路椎间盘切除椎间融合技术在长期随访中改善了临床结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f299/6901846/8583d38d7345/OAMJMS-7-2824-g001.jpg

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