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间歇性腹膜透析治疗终末期肾衰竭

Intermittent peritoneal dialysis in the treatment of end-stage renal failure.

作者信息

Walker R G, Atkins R C, Thomson N M, Scott D F

机构信息

Department of Nephrology, Prince Henry's Hospital, Melbourne.

出版信息

Med J Aust. 1979 Oct 20;2(8):393-7. doi: 10.5694/j.1326-5377.1979.tb104204.x.

DOI:10.5694/j.1326-5377.1979.tb104204.x
PMID:318461
Abstract

Our experience of 54 patients with end-stage renal failure, who were treated with intermittent peritoneal dialysis and compared with patients maintained by haemodialysis over the years 1972 to 1978, has been reviewed. All patients received peritoneal dialysis for more than six weeks. The total experience was 32.8 patient dialysis-years, 48% as home dialysis. Peritoneal dialysis was used as an interim procedure in 19 patients who were waiting for haemodialysis. However, in 35 patients (particularly in the very young and elderly, and in situations of poor social support), recurrent peritoneal dialysis was chosen as the definitive dialysis therapy. Dialysis was assessed as "adequate" in all, but two, patients. The major complication of peritoneal dialysis was peritonitis, although its over-all incidence of 1.31 episodes per patient dialysis-year was low. An attack of peritonitis occurred every nine months of patient exposure, though the incidence of bacterial peritonitis averaged only once every 26 months. Fifty per cent of patients never had an episode of peritonitis. Intermittent peritoneal dialysis was associated with greater morbidity and mortality than haemodialysis, perhaps due, in part, to the older age of the peritoneal dialysis group. Intermittent peritoneal dialysis is a valuable adjunct to haemodialysis and transplantation in the treatment of end-stage renal failure.

摘要

我们回顾了1972年至1978年间54例终末期肾衰竭患者的治疗经验,这些患者接受间歇性腹膜透析治疗,并与同期接受血液透析维持治疗的患者进行了比较。所有患者均接受腹膜透析超过六周。总治疗经验为32.8患者透析年,其中48%为家庭透析。腹膜透析被用作19例等待血液透析患者的过渡治疗手段。然而,在35例患者中(尤其是非常年轻和年老的患者,以及社会支持较差的情况下),反复腹膜透析被选为最终的透析治疗方法。除两名患者外,所有患者的透析均被评估为“充分”。腹膜透析的主要并发症是腹膜炎,尽管其总体发生率为每患者透析年1.31次,发生率较低。每9个月的患者暴露会发生一次腹膜炎发作,不过细菌性腹膜炎的发生率平均每26个月仅一次。50%的患者从未发生过腹膜炎发作。间歇性腹膜透析与血液透析相比,发病率和死亡率更高,这可能部分归因于腹膜透析组患者年龄较大。间歇性腹膜透析是血液透析和移植治疗终末期肾衰竭的一种有价值的辅助手段。

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