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[低功率七步法双叶钬激光前列腺剜除术治疗良性前列腺增生症的手术技术]

[Low power seven-step two-lobe holmium laser enucleation of the prostate technique for surgical treatment of benign prostatic hyperplasia].

作者信息

Liu K, Zhang F, Xiao C L, Xia H Z, Hao Y C, Bi H, Zhao L, Liu Y Q, Lu J, Ma L L

机构信息

Department of Urology, Peking University Third Hospital, Beijing 100191, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2019 Dec 18;51(6):1159-1164. doi: 10.19723/j.issn.1671-167X.2019.06.032.

Abstract

OBJECTIVE

To evaluate the safety and efficacy of the seven-step two-lobe holmium laser enucleation of the prostate (HoLEP) technique with low power laser device, and to introduce the detailed operating procedures, key points, short-term outcomes of this modified HoLEP technique.

METHODS

From March 2016 to November 2017, 90 patients underwent HoLEP in Peking University Third Hospital. The patients were divided into two groups: high-power group (32 patients) were performed with traditional Gilling's three-lobe enucleation using high power (90 W) laser; Low-power group (58 patients) were performed with seven-step two-lobe enucleation using low power (40 W) laser. The main steps of the low power seven-step two-lobe HoLEP phase included: (1) The identification of the correct plane between adenoma and capsule at 5 and 7 o'clock laterally to the veru montanum; (2) The connection of the bilateral plane by making a adenoma incision at the proximal point of veru montanum; (3) The extension of the dorsal plane under the whole three lobes between adenoma and capsule towards the bladder neck; (4) The separation of the middle lobe from two lateral lobes by making two retrograde incisions separately from apex 5 and 7 o'clock towards the bladder neck; (5) The enucleation of the middle lobe adenoma by extending the dorsal plane through into the bladder; (6) The prevention of the apex mucosa by making a circle incision at the apex of the prostate; (7) The en-bloc enucleation of the two lateral lobe adenomas by extending the lateral and ventral plane between adenoma and capsule from 5 and 7 o'clock to 12 o'clock conjunction and through into the bladder.

RESULTS

The mean patient age was (66.25±5.37) years vs. (68.00±5.18) years; The mean body mass indexes were (24.13±4.06) kg/m vs. (24.57±3.50) kg/m; The mean prostate specific antigen values were (3.23±2.47) μg/L vs. (6.00±6.09) μg/L; The average prostatic volumes evaluated by ultrasound was (49.03±20.63) mL vs. (67.55±36.97) mL. There was no significant difference between the two groups. Furthermore, there were no significant differences in terms of perioperative and follow up data, including operative time; enucleation efficiencies; hemoglobin decrease; blood sodium and potassiumthe change postoperatively; catheterization duration and hospital stay; the international prostate symptom scores and quality of life scores pre- and post-operatively. There was 1 transurethral resection of the prostate (TURP) conversion in high-power group and 1 transfusion in low-power group during the operations. The follow-up one month after operation showed no severe stress incontinence in both the groups, whereas 3 cases ejaculatory dysfunctions in high-power group versus 1 case in low-power group were observed; Other surgeryrelated complications included: 2 cases postoperative hemorrhage (Clavien II and Clavien IIIb) in high-power group, 2 cases postoperative temperature more than 38 °C (Clavien I) and 1 case dysuria following catheter removal (Clavien I) in low-power group.

CONCLUSION

Low power laser device can be applied safe and effectively for HoLEP procedure using the seven-step two-lobe HoLEP technique. The outcomes comparable with high power laser HoLEP can be achieved.

摘要

目的

评估使用低功率激光设备的七步法两叶钬激光前列腺剜除术(HoLEP)技术的安全性和有效性,并介绍这种改良HoLEP技术的详细操作步骤、要点及短期结果。

方法

2016年3月至2017年11月,90例患者在北京大学第三医院接受HoLEP手术。患者分为两组:高功率组(32例)采用传统的Gilling三步法三叶剜除术,使用高功率(90W)激光;低功率组(58例)采用七步法两叶剜除术,使用低功率(40W)激光。低功率七步法两叶HoLEP阶段的主要步骤包括:(1)在前列腺小囊外侧5点和7点处识别腺瘤与包膜之间的正确平面;(2)在前列腺小囊近端做腺瘤切口连接双侧平面;(3)在腺瘤与包膜之间的整个三叶下方将背侧平面延伸至膀胱颈;(4)分别从5点和7点尖部向膀胱颈做两条逆行切口,将中叶与两侧叶分离;(5)通过将背侧平面延伸至膀胱,剜除中叶腺瘤;(6)在前列腺尖部做环形切口,保护尖部黏膜;(7)将腺瘤与包膜之间的外侧和腹侧平面从5点和7点延伸至12点连接并延伸至膀胱,将两侧叶腺瘤整块剜除。

结果

两组患者的平均年龄分别为(66.25±5.37)岁和(68.00±5.18)岁;平均体重指数分别为(24.13±4.06)kg/m和(24.57±3.50)kg/m;平均前列腺特异性抗原值分别为(3.23±2.47)μg/L和(6.00±6.09)μg/L;超声评估的平均前列腺体积分别为(49.03±20.63)mL和(67.55±36.97)mL。两组之间无显著差异。此外,围手术期和随访数据,包括手术时间、剜除效率、血红蛋白下降、术后血钠和血钾变化、导尿持续时间和住院时间、术前和术后国际前列腺症状评分及生活质量评分,均无显著差异。高功率组手术中有1例转为经尿道前列腺切除术(TURP),低功率组有1例输血。术后1个月随访显示,两组均无严重压力性尿失禁,高功率组观察到3例射精功能障碍,低功率组观察到1例;其他手术相关并发症包括:高功率组2例术后出血(Clavien II和Clavien IIIb),低功率组2例术后体温超过38℃(Clavien I)和1例拔管后排尿困难(Clavien I)。

结论

低功率激光设备可安全有效地应用于七步法两叶HoLEP技术的HoLEP手术。可获得与高功率激光HoLEP相当的结果。

相似文献

本文引用的文献

1
High-power HoLEP: no thanks!高功率钬激光前列腺剜除术:不用了,谢谢!
World J Urol. 2018 May;36(5):837-838. doi: 10.1007/s00345-018-2186-x. Epub 2018 Jan 27.
7
HoLEP has come of age.经尿道前列腺剜除术已成熟。
World J Urol. 2015 Apr;33(4):487-93. doi: 10.1007/s00345-014-1443-x. Epub 2014 Nov 22.

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