Ardizzone E, Bonadonna F, Gaglio S, Marcenò R, Nicolini C, Ruggiero C, Sorbello F
Department of Electrical Engineering, Palermo, Italy.
Med Inform (Lond). 1988 Jul-Sep;13(3):199-210. doi: 10.3109/14639238809010100.
An artificial intelligence system, NEWCHEM, for the development of new oncology therapies is described. This system takes into account the most recent advances in molecular and cellular biology and in cell-drug interaction, and aims to guide experimentation in the design of new optimal protocols. Further work is being carried out, aimed to embody in the system all the basic knowledge of biology, physiopathology and pharmacology, to reason qualitatively from first principles so as to be able to suggest cancer therapies.
本文介绍了一种用于开发新型肿瘤治疗方法的人工智能系统——NEWCHEM。该系统考虑了分子与细胞生物学以及细胞-药物相互作用方面的最新进展,旨在指导新型优化方案设计中的实验。目前正在开展进一步的工作,目标是将生物学、生理病理学和药理学的所有基础知识融入该系统,以便能够从第一原理进行定性推理,从而提出癌症治疗方案。