Beliles R P, Makris S L, Ferguson F, Putman C, Sapanski W, Kelly N, Partymiller K, Heicklen J
Litton Bionetics, Inc., Kensington, Maryland 20795.
Environ Res. 1978 Oct;17(2):165-76. doi: 10.1016/0013-9351(78)90019-1.
Pregnant female mice were exposed from Days 6 to 17 of pregnancy to 8.9 +/- 2.0 ppm of diethylhydroxylamine and 14.3 +/- 2.0 ppm of nitroethane. Exposures were for 8.25 +/- 2.25 hours/day including weekends. The mice were also exposed continuously for 24 hours a day to the vapor of diethylamine hydrogen sulfite. The exposure produced no effect on the dams compared to the control group. There was no evidence of compound-induced terata, variation in sex ratio, embryotoxicity, or inhibition of fetal growth and development.
怀孕的雌性小鼠在怀孕第6天至第17天期间，暴露于浓度为8.9±2.0 ppm的二乙羟胺和14.3±2.0 ppm的硝基乙烷环境中。暴露时间为每天8.25±2.25小时，包括周末。这些小鼠还每天24小时持续暴露于亚硫酸氢二乙胺的蒸汽中。与对照组相比，该暴露对母鼠没有产生影响。没有证据表明存在化合物诱导的畸形、性别比例变化、胚胎毒性或对胎儿生长发育的抑制作用。
