胸腔内霍奇金淋巴瘤伴发的杵状指：一例报告
Digital clubbing occurring in intrathoracic Hodgkin lymphoma: A case report.
作者信息
Gai Xiaoyan, Yang Wei, Zhu Hong, Sun Yongchang
出版信息
Medicine (Baltimore). 2019 Dec;98(51):e18388. doi: 10.1097/MD.0000000000018388.
RATIONALE
Digital clubbing is rarely associated with lymphoma. This study reports a case of intrathoracic Hodgkin lymphoma with digital clubbing and reviews the current literature regarding the clinical characteristics of this condition.
PATIENT CONCERN
A 21-year-old woman presented with a 3-month history of cough and 1 month of fever, with apparent digital clubbing. A computed tomography (CT) scan of the lungs revealed a large pulmonary mass.
DIAGNOSIS
A CT-guided transthoracic needle biopsy was conducted. Pathology determined a diagnosis of Hodgkin lymphoma.
INTERVENTIONS
The patient underwent 6 courses of chemotherapy and intensification, followed by autografting.
OUTCOMES
The patient recovered and a complete hematological remission was obtained. The patient is alive with no evidence of disease 60 months after diagnosis, with the digital clubbing of the fingers and toes completely resolved.
CONCLUSION
Patients with digital clubbing and intrathoracic lesions need to be examined carefully to determine tumor malignancy.
理论依据
杵状指很少与淋巴瘤相关。本研究报告了一例伴有杵状指的胸腔内霍奇金淋巴瘤病例，并回顾了有关该病症临床特征的当前文献。
患者情况
一名21岁女性，有3个月咳嗽史和1个月发热史，伴有明显杵状指。肺部计算机断层扫描（CT）显示肺部有一个大肿块。
诊断
进行了CT引导下经胸针吸活检。病理诊断为霍奇金淋巴瘤。
干预措施
患者接受了6个疗程的化疗和强化治疗，随后进行了自体移植。
结果
患者康复，获得了完全血液学缓解。诊断60个月后患者存活，无疾病证据，手指和脚趾的杵状指完全消失。
结论
伴有杵状指和胸腔内病变的患者需要仔细检查以确定肿瘤的恶性程度。
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