Zhang Qian, Huang Ruihua, Ma Xiang, Jiang Nengjing, Zhou Wuduo, Gao Chen, Zhao Moran, Niu Peipei, Zhang Zongping, Li Qiang, Zhou Juan, Li Pinghua
Institute of Swine Science, Nanjing Agricultural University, Nanjing 210095, China.
Huaian Academy, Nanjing Agricultural University, Huaian 223005, China.
Animals (Basel). 2019 Dec 19;10(1):11. doi: 10.3390/ani10010011.
Eastern and Southern Chinese pigs have been imported to Western countries to improve economic traits including fertility in Western pig breeds by intensive selecting Chinese advantage genes. It was reported that the selected Asian-derived non-synonymous mutations including (G > T) in the aryl hydrocarbon receptor () gene could increase litter size in multiple European commercial lines. The objective of this study is to identify whether in the gene is polymorphic and has an influence on the litter size in 10 pig populations including five Chinese indigenous breeds, one cultivated breed, one lean-type breed, two North American lean-type breeds, and one European lean-type breed. We found that had polymorphism in all 10 populations, whereas was associated with litter size only in French Yorkshire (FRA-Y) and Chinese cultivated Suhuai (SH) pigs containing approximately 75% British Yorkshire pigs ancestry. Our results indicated that in the gene was a potential marker to improve litter size in European commercial lines and the pigs containing ancestries of European commercial lines, whereas this locus maybe not a causal mutation affecting the litter size but only in linkage disequilibrium with the causal mutation for litter size.
中国东部和南部的猪已被引入西方国家，通过密集选择中国的优势基因来改善包括西方猪种繁殖力在内的经济性状。据报道，在芳烃受体（AHR）基因中选择的源自亚洲的非同义突变（包括G>T）可增加多个欧洲商业品系的产仔数。本研究的目的是确定AHR基因中的该突变在10个猪群体中是否具有多态性并对产仔数有影响，这10个猪群体包括五个中国本土品种、一个培育品种、一个瘦肉型品种、两个北美瘦肉型品种和一个欧洲瘦肉型品种。我们发现该突变在所有10个群体中均具有多态性，而仅在含有约75%英国约克郡猪血统的法国约克郡（FRA-Y）和中国培育品种苏淮（SH）猪中与产仔数相关。我们的结果表明，AHR基因中的该突变是改善欧洲商业品系以及含有欧洲商业品系血统的猪产仔数的潜在标记，而该位点可能不是影响产仔数的因果突变，只是与产仔数的因果突变处于连锁不平衡状态。
